—In this paper, we present a space-time-frequency joint block coding (STFBC) scheme to exploit the essential space-time-frequency degrees of freedom of multiuser MISOMC-CDMA systems. Specifically, we use a series of orthogonal random codes to spread the space time code over several subcarriers to obtain multi-diversity gains, while multiuser parallel transmission is applied over the same sub-carriers by making use of multiple orthogonal code channels. Furthermore, to improve the system performance, we put forward to linear precoding to the predetermined orthogonal STFBC, including transmitting directions selection and power allocation over these directions. We propose a precoder design method by making use of channel statistical information in time domain based on the Kronecker correlation model for the channels, so feedback amount can be decreased largely in multi-carrier systems. In addition, we give the performance analysis from the perspectives of diversity order and coding gain...