We present a local learning rule in which Hebbian learning is conditional on an incorrect prediction of a reinforcement signal. We propose a biological interpretation of such a framework and display its utility through examples in which the reinforcement signal is cast as the delivery of a neuromodulator to its target. Three examples are presented which illustrate how this framework can be applied to the development of the oculomotor system.
P. Read Montague, Peter Dayan, Steven J. Nowlan, T