VANTED: A system for advanced data analysis and visualization in the context of biological networks

Background: Recent advances with high-throughput methods in life-science research have increased the need for automatized data analysis and visual exploration techniques. Sophisticated bioinformatics tools are essential to deduct biologically meaningful interpretations from the large amount of experimental data, and help to understand biological processes. Results: We present VANTED, a tool for the visualization and analysis of networks with related experimental data. Data from large-scale biochemical experiments is uploaded into the software via a Microsoft Excel-based form. Then it can be mapped on a network that is either drawn with the tool itself, downloaded from the KEGG Pathway database, or imported using standard network exchange formats. Transcript, enzyme, and metabolite data can be presented in the context of their underlying networks, e. g. metabolic pathways or classification hierarchies. Visualization and navigation methods support the visual exploration of the data-enri...

• Type: Journal
• Year: 2006
• Where: BMCBI
• Authors: Björn H. Junker, Christian Klukas, Falk Schreiber
• Keywords: BMCBI 2006, Correlation Networks, Tool, Visual Exploration