141
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16 years 3 months ago
2001 Springer 
The recent growth in genomic data and measurements of genome-wide expression patterns allows us to apply computational tools to examine gene regulation by transcription factors. I...
185
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16 years 3 months ago
2001 Springer
motif discovery problem abstracts the task of discovering short, conserved sites in genomic DNA. Pevzner and Sze recently described a precise combinatorial formulation of motif di...
90
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16 years 3 months ago
2001 Springer 
Phylogenetic footprinting is a comparative genomics approach for predicting transcription factor binding sites, where a set of orthologous regulatory regions are compared and short...
111
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16 years 3 months ago
2001 Springer 
In proteomics 2?dimensional gel electrophoresis (2?DE) is a separation technique for proteins. The resulting protein spots can be identified by either using picking robots and sub...
111
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16 years 3 months ago
2001 Springer
Hidden Markov models (HMMs) have been successfully applied to a variety of problems in molecular biology, ranging from alignment problems to gene nding and annotation. Alignment p...
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Computational Biology