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» A 3-D Self-Reconfigurable Structure
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BMCBI
2008
92views more  BMCBI 2008»
13 years 7 months ago
Proteochemometric modeling of HIV protease susceptibility
Background: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated ...
Maris Lapinsh, Martin Eklund, Ola Spjuth, Peteris ...
BMCBI
2007
107views more  BMCBI 2007»
13 years 7 months ago
Prediction of potential drug targets based on simple sequence properties
Background: During the past decades, research and development in drug discovery have attracted much attention and efforts. However, only 324 drug targets are known for clinical dr...
Qingliang Li, Luhua Lai
BMCBI
2010
123views more  BMCBI 2010»
13 years 7 months ago
An improved classification of G-protein-coupled receptors using sequence-derived features
Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
Zhen-Ling Peng, Jian-Yi Yang, Xin Chen
COMPLEXITY
2007
116views more  COMPLEXITY 2007»
13 years 7 months ago
Life, information, entropy, and time: Vehicles for semantic inheritance
abstractions provides an additional supra-phenotypic vehicle for semantic inheritance, which supports the cultural heritages around which civilizations revolve. The following three...
Antony R. Crofts
PRESENCE
2008
185views more  PRESENCE 2008»
13 years 7 months ago
Pilot Evaluation Study of a Virtual Paracentesis Simulator for Skill Training and Assessment: The Beneficial Effect of Haptic Di
Effective, real-time training of health care professionals in invasive procedures is a challenging task. Furthermore, assessing in practice the acquisition of the dexterity and sk...
Costas S. Tzafestas, Kostas Birbas, Yiannis Koumpo...