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BMCBI
2007

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Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing

14 years 18 days ago

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Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...

Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...

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Id	Views	Title	Status

1	265	Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing	claim
2	247	A survey of DNA motif finding algorithms	claim
3	246	TomoJ: tomography software for three-dimensional reconstruction in transmission electron microscopy	claim
4	239	Pre-processing Agilent microarray data	claim
5	237	FLAME, a novel fuzzy clustering method for the analysis of DNA microarray data	claim
6	233	160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)	claim
7	227	Growing functional modules from a seed protein via integration of protein interaction and gene expression data	claim
8	226	MiRFinder: an improved approach and software implementation for genome-wide fast microRNA precursor scans	claim
9	219	MetaQTL: a package of new computational methods for the meta-analysis of QTL mapping experiments	claim
10	218	Annotation and query of tissue microarray data using the NCI Thesaurus	claim
11	217	OntologyWidget - a reusable, embeddable widget for easily locating ontology terms	claim
12	217	On consensus biomarker selection	claim
13	216	A replica exchange Monte Carlo algorithm for protein folding in the HP model	claim
14	215	Learning causal networks from systems biology time course data: an effective model selection procedure for the vector autoregressive process	claim
15	209	SYMBIOmatics: Synergies in Medical Informatics and Bioinformatics - exploring current scientific literature for emerging topics	claim
16	207	Discovering biomarkers from gene expression data for predicting cancer subgroups using neural networks and relational fuzzy clustering	claim
17	207	Analyzing in situ gene expression in the mouse brain with image registration, feature extraction and block clustering	claim
18	203	A Grid-based solution for management and analysis of microarrays in distributed experiments	claim
19	202	ProtNet: a tool for stochastic simulations of protein interaction networks dynamics	claim
20	200	Assessment of algorithms for high throughput detection of genomic copy number variation in oligonucleotide microarray data	claim
21	200	BNDB - The Biochemical Network Database	claim
22	198	Correlation analysis reveals the emergence of coherence in the gene expression dynamics following system perturbation	claim
23	197	Boolean networks using the chi-square test for inferring large-scale gene regulatory networks	claim
24	195	NeuroTerrain - a client-server system for browsing 3D biomedical image data sets	claim
25	194	Kernel-imbedded Gaussian processes for disease classification using microarray gene expression data	claim
26	194	A meta-data based method for DNA microarray imputation	claim
27	190	Discriminative motif discovery in DNA and protein sequences using the DEME algorithm	claim
28	187	BioWMS: a web-based Workflow Management System for bioinformatics	claim
29	186	GeneBins: a database for classifying gene expression data, with application to plant genome arrays	claim
30	186	Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms	claim
31	185	GEDI: a user-friendly toolbox for analysis of large-scale gene expression data	claim
32	183	Considerations in the identification of functional RNA structural elements in genomic alignments	claim
33	182	Additive risk survival model with microarray data	claim
34	182	EDISA: extracting biclusters from multiple time-series of gene expression profiles	claim
35	182	Hybrid elementary flux analysis/nonparametric modeling: application for bioprocess control	claim
36	182	Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data	claim
37	181	ASMPKS: an analysis system for modular polyketide synthases	claim
38	181	Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases	claim
39	181	Versatile annotation and publication quality visualization of protein complexes using POLYVIEW-3D	claim
40	180	Using expression arrays for copy number detection: an example from E. coli	claim
41	180	Splicy: a web-based tool for the prediction of possible alternative splicing events from Affymetrix probeset data	claim
42	179	rMotifGen: random motif generator for DNA and protein sequences	claim
43	179	Automated smoother for the numerical decoupling of dynamics models	claim
44	179	Gene selection with multiple ordering criteria	claim
45	179	Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data	claim
46	178	SVM clustering	claim
47	177	The BioPrompt-box: an ontology-based clustering tool for searching in biological databases	claim
48	177	Biowep: a workflow enactment portal for bioinformatics applications	claim
49	176	Genome Expression Pathway Analysis Tool - Analysis and visualization of microarray gene expression data under genomic, proteomic and metabolic context	claim
50	176	The Firegoose: two-way integration of diverse data from different bioinformatics web resources with desktop applications	claim
51	176	Correlation-maximizing surrogate gene space for visual mining of gene expression patterns in developing barley endosperm tissue	claim
52	175	CLUSS: Clustering of protein sequences based on a new similarity measure	claim
53	175	Fast automated cell phenotype image classification	claim
54	175	Apollo2Go: a web service adapter for the Apollo genome viewer to enable distributed genome annotation	claim
55	174	Inferring activity changes of transcription factors by binding association with sorted expression profiles	claim
56	174	Normalization method for metabolomics data using optimal selection of multiple internal standards	claim
57	174	ESTuber db: an online database for Tuber borchii EST sequences	claim
58	173	Predicting state transitions in the transcriptome and metabolome using a linear dynamical system model	claim
59	173	Ringo - an R/Bioconductor package for analyzing ChIP-chip readouts	claim
60	173	CGKB: an annotation knowledge base for cowpea (Vigna unguiculata L.) methylation filtered genomic genespace sequences	claim
61	173	Recursive Cluster Elimination (RCE) for classification and feature selection from gene expression data	claim
62	172	msBayes: Pipeline for testing comparative phylogeographic histories using hierarchical approximate Bayesian computation	claim
63	172	Bayesian approaches to reverse engineer cellular systems: a simulation study on nonlinear Gaussian networks	claim
64	171	An open source infrastructure for managing knowledge and finding potential collaborators in a domain-specific subset of PubMed, with an example from human genome epidemiology	claim
65	171	Classification of microarray data using gene networks	claim
66	169	Transcriptional regulatory network refinement and quantification through kinetic modeling, gene expression microarray data and information theory	claim
67	169	The CRISPRdb database and tools to display CRISPRs and to generate dictionaries of spacers and repeats	claim
68	169	Transcription factor target prediction using multiple short expression time series from Arabidopsis thaliana	claim
69	168	Benchmarking consensus model quality assessment for protein fold recognition	claim
70	168	GOSim - an R-package for computation of information theoretic GO similarities between terms and gene products	claim
71	168	Automatic extraction of gene ontology annotation and its correlation with clusters in protein networks	claim
72	168	Advancing translational research with the Semantic Web	claim
73	168	Bayesian model-based inference of transcription factor activity	claim
74	167	Applying negative rule mining to improve genome annotation	claim
75	167	MindSeer: a portable and extensible tool for visualization of structural and functional neuroimaging data	claim
76	167	A stochastic differential equation model for transcriptional regulatory networks	claim
77	167	AlzPharm: integration of neurodegeneration data using RDF	claim
78	166	PathFinder: mining signal transduction pathway segments from protein-protein interaction networks	claim
79	166	Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics	claim
80	166	How to decide which are the most pertinent overly-represented features during gene set enrichment analysis	claim
81	166	Data handling strategies for high throughput pyrosequencers	claim
82	165	Direct maximum parsimony phylogeny reconstruction from genotype data	claim
83	165	TagSmart: analysis and visualization for yeast mutant fitness data measured by tag microarrays	claim
84	165	Ab initio identification of human microRNAs based on structure motifs	claim
85	165	Automatic reconstruction of a bacterial regulatory network using Natural Language Processing	claim
86	164	The Personal Sequence Database: a suite of tools to create and maintain web-accessible sequence databases	claim
87	164	SEARCHPATTOOL: a new method for mining the most specific frequent patterns for binding sites with application to prokaryotic DNA sequences	claim
88	164	Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks	claim
89	163	Strainer: software for analysis of population variation in community genomic datasets	claim
90	163	Use of genomic DNA control features and predicted operon structure in microarray data analysis: ArrayLeaRNA - a Bayesian approach	claim
91	163	A coherent graph-based semantic clustering and summarization approach for biomedical literature and a new summarization evaluation method	claim
92	162	Three-Dimensional Phylogeny Explorer: Distinguishing paralogs, lateral transfer, and violation of "molecular clock" assumption with 3D visualization	claim
93	162	Genome-wide identification of specific oligonucleotides using artificial neural network and computational genomic analysis	claim
94	162	Bioclipse: an open source workbench for chemo- and bioinformatics	claim
95	161	Efficient classification of complete parameter regions based on semidefinite programming	claim
96	160	Convergent algorithms for protein structural alignment	claim
97	160	Identifying protein complexes directly from high-throughput TAP data with Markov random fields	claim
98	160	Dendroscope: An interactive viewer for large phylogenetic trees	claim
99	160	Optimization based automated curation of metabolic reconstructions	claim
100	160	Establishing a major cause of discrepancy in the calibration of Affymetrix GeneChips	claim
101	159	sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database	claim
102	159	Detecting differential expression in microarray data: comparison of optimal procedures	claim
103	159	Computational genes: a tool for molecular diagnosis and therapy of aberrant mutational phenotype	claim
104	158	MetaLook: a 3D visualisation software for marine ecological genomics	claim
105	158	Penalized likelihood for sparse contingency tables with an application to full-length cDNA libraries	claim
106	157	Impact of image segmentation on high-content screening data quality for SK-BR-3 cells	claim
107	157	A hybrid multiscale Monte Carlo algorithm (HyMSMC) to cope with disparity in time scales and species populations in intracellular networks	claim
108	157	Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory	claim
109	157	Improving gene set analysis of microarray data by SAM-GS	claim
110	157	Statistical learning of peptide retention behavior in chromatographic separations: a new kernel-based approach for computational proteomics	claim
111	156	Large-scale clustering of CAGE tag expression data	claim
112	156	Accuracy of structure-based sequence alignment of automatic methods	claim
113	156	Bio: : NEXUS: a Perl API for the NEXUS format for comparative biological data	claim
114	156	Predictive modeling of plant messenger RNA polyadenylation sites	claim
115	155	ProMEX: a mass spectral reference database for proteins and protein phosphorylation sites	claim
116	155	Current approaches to gene regulatory network modelling	claim
117	155	ProCMD: a database and 3D web resource for protein C mutants	claim
118	154	Cinteny: flexible analysis and visualization of synteny and genome rearrangements in multiple organisms	claim
119	154	Classification of heterogeneous microarray data by maximum entropy kernel	claim
120	154	Bounds on the distribution of the number of gaps when circles and lines are covered by fragments: Theory and practical application to genomic and metagenomic projects	claim
121	154	PepBank - a database of peptides based on sequence text mining and public peptide data sources	claim
122	154	h-Profile plots for the discovery and exploration of patterns in gene expression data with an application to time course data	claim
123	154	Inferring biological networks with output kernel trees	claim
124	153	Can Clustal-style progressive pairwise alignment of multiple sequences be used in RNA secondary structure prediction?	claim
125	153	An exploration of alternative visualisations of the basic helix-loop-helix protein interaction network	claim
126	153	Estimating genealogies from linked marker data: a Bayesian approach	claim
127	153	MPHASYS: a mouse phenotype analysis system	claim
128	153	Lower bounds on multiple sequence alignment using exact 3-way alignment	claim
129	153	A new pairwise kernel for biological network inference with support vector machines	claim
130	153	Analysis of nanopore detector measurements using Machine-Learning methods, with application to single-molecule kinetic analysis	claim
131	152	PASSIM - an open source software system for managing information in biomedical studies	claim
132	152	A cross-species alignment tool (CAT)	claim
133	152	Bioinformatic identification of novel putative photoreceptor specific cis-elements	claim
134	152	A multiresolution approach to automated classification of protein subcellular location images	claim
135	152	Difference-based clustering of short time-course microarray data with replicates	claim
136	152	Recodon: Coalescent simulation of coding DNA sequences with recombination, migration and demography	claim
137	151	A statistical method to incorporate biological knowledge for generating testable novel gene regulatory interactions from microarray experiments	claim
138	151	Minimus: a fast, lightweight genome assembler	claim
139	151	A comparison study on algorithms of detecting long forms for short forms in biomedical text	claim
140	151	The Genopolis Microarray Database	claim
141	151	Identification of hot regions in protein-protein interactions by sequential pattern mining	claim
142	150	Refining intra-protein contact prediction by graph analysis	claim
143	149	A unified framework for finding differentially expressed genes from microarray experiments	claim
144	149	Novel and simple transformation algorithm for combining microarray data sets	claim
145	149	SAMPI: Protein Identification with Mass Spectra Alignments	claim
146	149	Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors	claim
147	149	Robust imputation method for missing values in microarray data	claim
148	148	Evaluation of gene-expression clustering via mutual information distance measure	claim
149	148	BPhyOG: An interactive server for genome-wide inference of bacterial phylogenies based on overlapping genes	claim
150	148	Toward the automated generation of genome-scale metabolic networks in the SEED	claim
151	148	Blast sampling for structural and functional analyses	claim
152	148	fREDUCE: Detection of degenerate regulatory elements using correlation with expression	claim
153	148	Computation of significance scores of unweighted Gene Set Enrichment Analyses	claim
154	148	WeederH: an algorithm for finding conserved regulatory motifs and regions in homologous sequences	claim
155	148	p53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray data	claim
156	147	MaxAlign: maximizing usable data in an alignment	claim
157	147	Statistical analysis and significance testing of serial analysis of gene expression data using a Poisson mixture model	claim
158	147	Hon-yaku: a biology-driven Bayesian methodology for identifying translation initiation sites in prokaryotes	claim
159	147	Predicting combinatorial binding of transcription factors to regulatory elements in the human genome by association rule mining	claim
160	147	Improved residue contact prediction using support vector machines and a large feature set	claim
161	147	Statistical significance of quantitative PCR	claim
162	147	Modeling biochemical transformation processes and information processing with Narrator	claim
163	147	Bias in random forest variable importance measures: Illustrations, sources and a solution	claim
164	147	Comparative analysis of long DNA sequences by per element information content using different contexts	claim
165	146	Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data	claim
166	146	Spatial location and its relevance for terminological inferences in bio-ontologies	claim
167	146	PubMed related articles: a probabilistic topic-based model for content similarity	claim
168	146	Towards Semantic e-Science for Traditional Chinese Medicine	claim
169	145	Colony size measurement of the yeast gene deletion strains for functional genomics	claim
170	145	Genome bioinformatic analysis of nonsynonymous SNPs	claim
171	145	BioPP: a tool for web-publication of biological networks	claim
172	145	Improved benchmarks for computational motif discovery	claim
173	145	The utility of MAS5 expression summary and detection call algorithms	claim
174	144	Robust regression for periodicity detection in non-uniformly sampled time-course gene expression data	claim
175	144	Application of amino acid occurrence for discriminating different folding types of globular proteins	claim
176	144	Gene analogue finder: a GRID solution for finding functionally analogous gene products	claim
177	144	Spectral estimation in unevenly sampled space of periodically expressed microarray time series data	claim
178	144	Motif kernel generated by genetic programming improves remote homology and fold detection	claim
179	144	Accelerated search for biomolecular network models to interpret high-throughput experimental data	claim
180	144	InPrePPI: an integrated evaluation method based on genomic context for predicting protein-protein interactions in prokaryotic genomes	claim
181	144	Assessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study analyzing the neurotransmitter/Na+ symporter family	claim
182	144	Automatic delineation of malignancy in histopathological head and neck slides	claim
183	143	RNAspa: a shortest path approach for comparative prediction of the secondary structure of ncRNA molecules	claim
184	143	Factor analysis for gene regulatory networks and transcription factor activity profiles	claim
185	143	An adaptive bin framework search method for a beta-sheet protein homopolymer model	claim
186	143	Gene selection for classification of microarray data based on the Bayes error	claim
187	142	Improving model construction of profile HMMs for remote homology detection through structural alignment	claim
188	142	Support Vector Machine-based method for predicting subcellular localization of mycobacterial proteins using evolutionary information and motifs	claim
189	142	Predicting and improving the protein sequence alignment quality by support vector regression	claim
190	142	SABERTOOTH: protein structural alignment based on a vectorial structure representation	claim
191	142	LinkHub: a Semantic Web system that facilitates cross-database queries and information retrieval in proteomics	claim
192	141	Reconstruction of human protein interolog network using evolutionary conserved network	claim
193	141	HeliCis: a DNA motif discovery tool for colocalized motif pairs with periodic spacing	claim
194	141	Artificial neural network models for prediction of intestinal permeability of oligopeptides	claim
195	141	A novel approach to detect hot-spots in large-scale multivariate data	claim
196	141	Using structural motif descriptors for sequence-based binding site prediction	claim
197	141	On the origin and evolution of biosynthetic pathways: integrating microarray data with structure and organization of the Common Pathway genes	claim
198	140	From genes to functional classes in the study of biological systems	claim
199	140	Prediction potential of candidate biomarker sets identified and validated on gene expression data from multiple datasets	claim
200	140	Investigations into the relationship between feedback loops and functional importance of a signal transduction network based on Boolean network modeling	claim
201	140	Accurate prediction of protein secondary structure and solvent accessibility by consensus combiners of sequence and structure information	claim
202	140	Evaluation of high-throughput functional categorization of human disease genes	claim
203	139	Improving model predictions for RNA interference activities that use support vector machine regression by combining and filtering features	claim
204	139	Bioinformatics analysis of the early inflammatory response in a rat thermal injury model	claim
205	139	XSTREAM: A practical algorithm for identification and architecture modeling of tandem repeats in protein sequences	claim
206	139	Significance analysis of microarray transcript levels in time series experiments	claim
207	138	Fast computation of distance estimators	claim
208	138	A full Bayesian hierarchical mixture model for the variance of gene differential expression	claim
209	138	A systematic approach to detecting transcription factors in response to environmental stresses	claim
210	138	A novel Bayesian approach to quantify clinical variables and to determine their spectroscopic counterparts in 1H NMR metabonomic data	claim
211	137	GEVALT: An integrated software tool for genotype analysis	claim
212	137	Bayesian refinement of protein functional site matching	claim
213	137	PlnTFDB: an integrative plant transcription factor database	claim
214	136	Genomorama: genome visualization and analysis	claim
215	136	Reduced modeling of signal transduction - a modular approach	claim
216	136	Automating document classification for the Immune Epitope Database	claim
217	136	Comparison of protein structures by growing neighborhood alignments	claim
218	136	Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees	claim
219	135	Detecting multivariate differentially expressed genes	claim
220	135	Measuring similarities between gene expression profiles through new data transformations	claim
221	135	DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput gene functional analysis	claim
222	135	RECOVIR: An application package to automatically identify some single stranded RNA viruses using capsid protein residues that uniquely distinguish among these viruses	claim
223	135	Sequence similarity is more relevant than species specificity in probabilistic backtranslation	claim
224	135	LIMPIC: a computational method for the separation of protein MALDI-TOF-MS signals from noise	claim
225	135	UbiProt: a database of ubiquitylated proteins	claim
226	135	Automatic extraction of reliable regions from multiple sequence alignments	claim
227	134	Automatic generation of 3D motifs for classification of protein binding sites	claim
228	134	Benchmarking natural-language parsers for biological applications using dependency graphs	claim
229	134	A framework for significance analysis of gene expression data using dimension reduction methods	claim
230	134	PLAN: a web platform for automating high-throughput BLAST searches and for managing and mining results	claim
231	134	Nearest Neighbor Networks: clustering expression data based on gene neighborhoods	claim
232	134	Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign	claim
233	133	Semantic integration to identify overlapping functional modules in protein interaction networks	claim
234	133	GenMAPP 2: new features and resources for pathway analysis	claim
235	133	MATLIGN: a motif clustering, comparison and matching tool	claim
236	133	AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides	claim
237	133	An efficient pseudomedian filter for tiling microrrays	claim
238	133	Semi-supervised learning for the identification of syn-expressed genes from fused microarray and in situ image data	claim
239	132	TPRpred: a tool for prediction of TPR-, PPR- and SEL1-like repeats from protein sequences	claim
240	132	On the analysis of glycomics mass spectrometry data via the regularized area under the ROC curve	claim
241	132	Analysis of probe level patterns in Affymetrix microarray data	claim
242	132	Dependence of paracentric inversion rate on tract length	claim
243	131	FUNC: a package for detecting significant associations between gene sets and ontological annotations	claim
244	131	On the detection of functionally coherent groups of protein domains with an extension to protein annotation	claim
245	131	ISHAPE: new rapid and accurate software for haplotyping	claim
246	131	Prediction of peptides observable by mass spectrometry applied at the experimental set level	claim
247	131	An improved method for identifying functionally linked proteins using phylogenetic profiles	claim
248	130	Exploiting residue-level and profile-level interface propensities for usage in binding sites prediction of proteins	claim
249	130	A robust measure of correlation between two genes on a microarray	claim
250	130	HMM-ModE - Improved classification using profile hidden Markov models by optimising the discrimination threshold and modifying emission probabilities with negative training sequences	claim
251	130	A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression data	claim
252	130	Reproducibility of microarray data: a further analysis of microarray quality control (MAQC) data	claim
253	130	Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base	claim
254	130	Differential analysis for high density tiling microarray data	claim
255	129	HoughFeature, a novel method for assessing drug effects in three-color cDNA microarray experiments	claim
256	129	A novel approach to sequence validating protein expression clones with automated decision making	claim
257	129	Integrated network reconstruction, visualization and analysis using YANAsquare	claim
258	129	Algebraic correction methods for computational assessment of clone overlaps in DNA fingerprint mapping	claim
259	129	Exploring inconsistencies in genome-wide protein function annotations: a machine learning approach	claim
260	129	Inferring cellular networks - a review	claim
261	128	Absolute estimation of initial concentrations of amplicon in a real-time RT-PCR process	claim
262	128	A Bayesian nonparametric method for prediction in EST analysis	claim
263	128	Compression-based classification of biological sequences and structures via the Universal Similarity Metric: experimental assessment	claim
264	128	Detailed estimation of bioinformatics prediction reliability through the Fragmented Prediction Performance Plots	claim
265	128	Combining classifiers to predict gene function in Arabidopsis thaliana using large-scale gene expression measurements	claim
266	128	Userscripts for the Life Sciences	claim
267	128	Model order selection for bio-molecular data clustering	claim
268	128	A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand binding sites	claim
269	127	A Latent Variable Approach for Meta-Analysis of Gene Expression Data from Multiple Microarray Experiments	claim
270	127	Characterization of protein-interaction networks in tumors	claim
271	127	The EIPeptiDi tool: enhancing peptide discovery in ICAT-based LC MS/MS experiments	claim
272	127	PARPs database: A LIMS systems for protein-protein interaction data mining or laboratory information management system	claim
273	127	Characterization and simulation of cDNA microarray spots using a novel mathematical model	claim
274	127	Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines	claim
275	127	CORRIE: enzyme sequence annotation with confidence estimates	claim
276	126	Including probe-level uncertainty in model-based gene expression clustering	claim
277	126	High-throughput identification of interacting protein-protein binding sites	claim
278	126	Reconstruction of cell population dynamics using CFSE	claim
279	126	Multiple non-collinear TF-map alignments of promoter regions	claim
280	126	Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation of Escherichia coli	claim
281	126	Comparison of gene expression profiles altered by comfrey and riddelliine in rat liver	claim
282	125	Statistical tests to compare motif count exceptionalities	claim
283	125	Bayesian meta-analysis models for microarray data: a comparative study	claim
284	125	Identification of discriminative characteristics for clusters from biologic data with InforBIO software	claim
285	124	Analysis on multi-domain cooperation for predicting protein-protein interactions	claim
286	124	A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality	claim
287	124	BioInfer: a corpus for information extraction in the biomedical domain	claim
288	124	BranchClust: a phylogenetic algorithm for selecting gene families	claim
289	124	CRISPR Recognition Tool (CRT): a tool for automatic detection of clustered regularly interspaced palindromic repeats	claim
290	124	Protein structural similarity search by Ramachandran codes	claim
291	123	PedGenie: meta genetic association testing in mixed family and case-control designs	claim
292	123	Tracembler - software for in-silico chromosome walking in unassembled genomes	claim
293	123	Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data	claim
294	123	BIRCH: A user-oriented, locally-customizable, bioinformatics system	claim
295	123	Normalization and experimental design for ChIP-chip data	claim
296	123	GO for gene documents	claim
297	123	Metabonomics evaluations of age-related changes in the urinary compositions of male Sprague Dawley rats and effects of data normalization methods on statistical and quantitative analysis	claim
298	123	Robust clustering in high dimensional data using statistical depths	claim
299	122	TAP score: torsion angle propensity normalization applied to local protein structure evaluation	claim
300	122	Dissecting complex transcriptional responses using pathway-level scores based on prior information	claim
301	121	Development of an epitope conservancy analysis tool to facilitate the design of epitope-based diagnostics and vaccines	claim
302	121	A procedure for identifying homologous alternative splicing events	claim
303	121	Predicting zinc binding at the proteome level	claim
304	121	A constrained polynomial regression procedure for estimating the local False Discovery Rate	claim
305	121	e-Science and biological pathway semantics	claim
306	120	Re-sampling strategy to improve the estimation of number of null hypotheses in FDR control under strong correlation structures	claim
307	120	Phylo-mLogo: an interactive and hierarchical multiple-logo visualization tool for alignment of many sequences	claim
308	120	Recognition of interferon-inducible sites, promoters, and enhancers	claim
309	120	Non-coding sequence retrieval system for comparative genomic analysis of gene regulatory elements	claim
310	120	Quantitative sequence-function relationships in proteins based on gene ontology	claim
311	120	Transcript-based redefinition of grouped oligonucleotide probe sets using AceView: High-resolution annotation for microarrays	claim
312	120	Computational analyses of eukaryotic promoters	claim
313	119	A dynamic programming approach for the alignment of signal peaks in multiple gas chromatography-mass spectrometry experiments	claim
314	119	Conceptual-level workflow modeling of scientific experiments using NMR as a case study	claim
315	119	Efficacy of different protein descriptors in predicting protein functional families	claim
316	118	A topological algorithm for identification of structural domains of proteins	claim
317	118	A new advance in alternative splicing databases: from catalogue to detailed analysis of regulation of expression and function of human alternative splicing variants	claim
318	117	Influence of degree correlations on network structure and stability in protein-protein interaction networks	claim
319	117	DNA-based watermarks using the DNA-Crypt algorithm	claim
320	117	Supervised multivariate analysis of sequence groups to identify specificity determining residues	claim
321	117	Application of a correlation correction factor in a microarray cross-platform reproducibility study	claim
322	117	Meta-analysis of several gene lists for distinct types of cancer: A simple way to reveal common prognostic markers	claim
323	116	Ranked Adjusted Rand: integrating distance and partition information in a measure of clustering agreement	claim
324	116	primetv: a viewer for reconciled trees	claim
325	116	Linear array of conserved sequence motifs to discriminate protein subfamilies: study on pyridine nucleotide-disulfide reductases	claim
326	116	MED: a new non-supervised gene prediction algorithm for bacterial and archaeal genomes	claim
327	116	Cloning, analysis and functional annotation of expressed sequence tags from the Earthworm Eisenia fetida	claim
328	116	Clustering protein environments for function prediction: finding PROSITE motifs in 3D	claim
329	115	Comparing sequences without using alignments: application to HIV/SIV subtyping	claim
330	115	How accurate and statistically robust are catalytic site predictions based on closeness centrality?	claim
331	115	Recognizing protein-protein interfaces with empirical potentials and reduced amino acid alphabets	claim
332	115	Correlation between structure and temperature in prokaryotic metabolic networks	claim
333	115	Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry	claim
334	115	A novel, fast, HMM-with-Duration implementation - for application with a new, pattern recognition informed, nanopore detector	claim
335	115	Local comparison of protein structures highlights cases of convergent evolution in analogous functional sites	claim
336	115	SpliceMiner: a high-throughput database implementation of the NCBI Evidence Viewer for microarray splice variant analysis	claim
337	114	Mining and state-space modeling and verification of sub-networks from large-scale biomolecular networks	claim
338	114	Probabilistic prediction and ranking of human protein-protein interactions	claim
339	114	Large scale statistical inference of signaling pathways from RNAi and microarray data	claim
340	114	False occurrences of functional motifs in protein sequences highlight evolutionary constraints	claim
341	114	Combination of scoring schemes for protein docking	claim
342	114	Gene models from ESTs (GeneModelEST): an application on the Solanum lycopersicum genome	claim
343	113	Bayesian Orthogonal Least Squares (BOLS) algorithm for reverse engineering of gene regulatory networks	claim
344	113	miRAS: a data processing system for miRNA expression profiling study	claim
345	113	CoryneRegNet 4.0 - A reference database for corynebacterial gene regulatory networks	claim
346	113	Hinge Atlas: relating protein sequence to sites of structural flexibility	claim
347	113	In silico panning for a non-competitive peptide inhibitor	claim
348	113	PILER-CR: Fast and accurate identification of CRISPR repeats	claim
349	113	Statistical power of phylo-HMM for evolutionarily conserved element detection	claim
350	113	Analysis and prediction of antibacterial peptides	claim
351	113	Statistical tools for transgene copy number estimation based on real-time PCR	claim
352	113	Learning biophysically-motivated parameters for alpha helix prediction	claim
353	112	Integrated olfactory receptor and microarray gene expression databases	claim
354	112	PFAAT version 2.0: A tool for editing, annotating, and analyzing multiple sequence alignments	claim
355	112	AUG_hairpin: prediction of a downstream secondary structure influencing the recognition of a translation start site	claim
356	112	Selecting dissimilar genes for multi-class classification, an application in cancer subtyping	claim
357	112	Inferring biological functions and associated transcriptional regulators using gene set expression coherence analysis	claim
358	111	Novel definition files for human GeneChips based on GeneAnnot	claim
359	111	Modular co-evolution of metabolic networks	claim
360	111	MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs	claim
361	111	CATMA, a comprehensive genome-scale resource for silencing and transcript profiling of Arabidopsis genes	claim
362	110	Analysis of feedback loops and robustness in network evolution based on Boolean models	claim
363	110	Interpretation of multiple probe sets mapping to the same gene in Affymetrix GeneChips	claim
364	110	Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy	claim
365	109	Seahawk: moving beyond HTML in Web-based bioinformatics analysis	claim
366	109	A domain-based approach to predict protein-protein interactions	claim
367	109	TABASCO: A single molecule, base-pair resolved gene expression simulator	claim
368	109	Towards a comprehensive structural coverage of completed genomes: a structural genomics viewpoint	claim
369	109	Computational RNA secondary structure design: empirical complexity and improved methods	claim
370	109	A cis-regulatory logic simulator	claim
371	109	Discarding duplicate ditags in LongSAGE analysis may introduce significant error	claim
372	108	Publishing perishing? Towards tomorrow's information architecture	claim
373	108	Integrating sequence and structural biology with DAS	claim
374	108	Computer-aided identification of polymorphism sets diagnostic for groups of bacterial and viral genetic variants	claim
375	108	Design and implementation of a generalized laboratory data model	claim
376	107	Prediction of potential drug targets based on simple sequence properties	claim
377	107	antiCODE: a natural sense-antisense transcripts database	claim
378	107	Reuse of structural domain-domain interactions in protein networks	claim
379	107	OReFiL: an online resource finder for life sciences	claim
380	107	Progressive multiple sequence alignments from triplets	claim
381	107	A general and efficient method for estimating continuous IBD functions for use in genome scans for QTL	claim
382	107	Linking microarray reporters with protein functions	claim
383	107	A computational approach for detecting peptidases and their specific inhibitors at the genome level	claim
384	106	Constructing a meaningful evolutionary average at the phylogenetic center of mass	claim
385	106	In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells	claim
386	106	Improved classification accuracy in 1- and 2-dimensional NMR metabolomics data using the variance stabilising generalised logarithm transformation	claim
387	106	Mining prokaryotic genomes for unknown amino acids: a stop-codon-based approach	claim
388	106	Modeling SAGE tag formation and its effects on data interpretation within a Bayesian framework	claim
389	106	Discovering functional linkages and uncharacterized cellular pathways using phylogenetic profile comparisons: a comprehensive assessment	claim
390	106	Simultaneous identification of long similar substrings in large sets of sequences	claim
391	106	The AnnoLite and AnnoLyze programs for comparative annotation of protein structures	claim
392	105	HoxPred: automated classification of Hox proteins using combinations of generalised profiles	claim
393	105	Generating confidence intervals on biological networks	claim
394	105	Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor stimulation	claim
395	105	Predicting RNA secondary structure by the comparative approach: how to select the homologous sequences	claim
396	105	VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines	claim
397	105	Extended analysis of benchmark datasets for Agilent two-color microarrays	claim
398	105	Constrained hidden Markov models for population-based haplotyping	claim
399	105	Finding regulatory elements and regulatory motifs: a general probabilistic framework	claim
400	104	Comparative evaluation of gene-set analysis methods	claim
401	104	Predicting active site residue annotations in the Pfam database	claim
402	104	Joint mapping of genes and conditions via multidimensional unfolding analysis	claim
403	104	Identification of putative regulatory upstream ORFs in the yeast genome using heuristics and evolutionary conservation	claim
404	104	TISs-ST: a web server to evaluate polymorphic translation initiation sites and their reflections on the secretory targets	claim
405	104	A comparison of Affymetrix gene expression arrays	claim
406	104	A response to Yu et al. "A forward-backward fragment assembling algorithm for the identification of genomic amplification and deletion breakpoints using high-density single nucleotide polymorp	claim
407	104	Using contextual and lexical features to restructure and validate the classification of biomedical concepts	claim
408	104	Validating module network learning algorithms using simulated data	claim
409	103	A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance	claim
410	103	Dynamic simulation of regulatory networks using SQUAD	claim
411	103	eQTL Viewer: visualizing how sequence variation affects genome-wide transcription	claim
412	103	Systems biology approach for mapping the response of human urothelial cells to infection by Enterococcus faecalis	claim
413	103	Nanopore-based kinetics analysis of individual antibody-channel and antibody-antigen interactions	claim
414	103	Cross platform microarray analysis for robust identification of differentially expressed genes	claim
415	103	Shared transcriptional correlations in seed formation and in plants response to drought	claim
416	102	FlexOracle: predicting flexible hinges by identification of stable domains	claim
417	102	A comprehensive system for evaluation of remote sequence similarity detection	claim
418	102	Multivariate Analysis and Visualization of Splicing Correlations in Single-Gene Transcriptomes	claim
419	102	Identification of homologs in insignificant blast hits by exploiting extrinsic gene properties	claim
420	102	Understanding and using the meaning of statements in a bio-ontology: recasting the Gene Ontology in OWL	claim
421	102	qPIPSA: Relating enzymatic kinetic parameters and interaction fields	claim
422	102	Setting up a large set of protein-ligand PDB complexes for the development and validation of knowledge-based docking algorithms	claim
423	102	A mixture of feature experts approach for protein-protein interaction prediction	claim
424	102	The MEPS server for identifying protein conformational epitopes	claim
425	101	Relationship between insertion/deletion (indel) frequency of proteins and essentiality	claim
426	101	Statistical validation of megavariate effects in ASCA	claim
427	101	Subcellular location prediction of proteins using support vector machines with alignment of block sequences utilizing amino acid composition	claim
428	101	Robust detection and verification of linear relationships to generate metabolic networks using estimates of technical errors	claim
429	101	Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats	claim
430	100	SBMLeditor: effective creation of models in the Systems Biology Markup Language (SBML)	claim
431	100	PARE: A tool for comparing protein abundance and mRNA expression data	claim
432	100	Discovering structural motifs using a structural alphabet: Application to magnesium-binding sites	claim
433	100	Bioinformatics in Italy: BITS2006, the third annual meeting of the Italian Society of Bioinformatics	claim
434	99	Identifying allosteric fluctuation transitions between different protein conformational states as applied to Cyclin Dependent Kinase 2	claim
435	99	Flexible mapping of homology onto structure with Homolmapper	claim
436	99	Orthogonal projections to latent structures as a strategy for microarray data normalization	claim
437	99	Statistical significance of cis-regulatory modules	claim
438	99	The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data	claim
439	99	RepSeq - A database of amino acid repeats present in lower eukaryotic pathogens	claim
440	99	Stratification bias in low signal microarray studies	claim
441	99	Prediction of MHC class II binding affinity using SMM-align, a novel stabilization matrix alignment method	claim
442	99	Towards validating the hypothesis of phylogenetic profiling	claim
443	98	Evaluation of 3D-Jury on CASP7 models	claim
444	98	Duration learning for analysis of nanopore ionic current blockades	claim
445	97	A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficient	claim
446	97	In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation	claim
447	97	A verification protocol for the probe sequences of Affymetrix genome arrays reveals high probe accuracy for studies in mouse, human and rat	claim
448	97	SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets	claim
449	97	Relating destabilizing regions to known functional sites in proteins	claim
450	96	Protein subcellular localization prediction based on compartment-specific features and structure conservation	claim
451	96	Analysis of the role of retrotransposition in gene evolution in vertebrates	claim
452	96	Features generated for computational splice-site prediction correspond to functional elements	claim
453	96	Structure and function predictions of the Msa protein in Staphylococcus aureus	claim
454	95	Phylogenetic tree information aids supervised learning for predicting protein-protein interaction based on distance matrices	claim
455	95	ZPS: visualization of recent adaptive evolution of proteins	claim
456	95	Haplotype-based score test for linkage in nuclear families	claim
457	95	ASH structure alignment package: Sensitivity and selectivity in domain classification	claim
458	95	Supervised group Lasso with applications to microarray data analysis	claim
459	95	Logical modelling and analysis of the budding yeast cell cycle	claim
460	95	Methods for estimating human endogenous retrovirus activities from EST databases	claim
461	94	Lightweight genome viewer: portable software for browsing genomics data in its chromosomal context	claim
462	94	False positive reduction in protein-protein interaction predictions using gene ontology annotations	claim
463	94	An evolutionary method for learning HMM structure: prediction of protein secondary structure	claim
464	94	A Hidden Markov Model to estimate population mixture and allelic copy-numbers in cancers using Affymetrix SNP arrays	claim
465	94	Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX'	claim
466	94	A structural analysis of in vitro catalytic activities of hammerhead ribozymes	claim
467	94	Model based analysis of real-time PCR data from DNA binding dye protocols	claim
468	94	Transcriptional regulation at a glance	claim
469	93	Representing default knowledge in biomedical ontologies: application to the integration of anatomy and phenotype ontologies	claim
470	93	The topology of metabolic isotope labeling networks	claim
471	93	SVM-Fold: a tool for discriminative multi-class protein fold and superfamily recognition	claim
472	92	Large-scale validation of methods for cytotoxic T-lymphocyte epitope prediction	claim
473	92	Probabilistic modeling and machine learning in structural and systems biology	claim
474	92	Nanopore current transduction analysis of protein binding to non-terminal and terminal DNA regions: analysis of transcription factor binding, retroviral DNA terminus dynamics, and retroviral i	claim
475	91	A mass accuracy sensitive probability based scoring algorithm for database searching of tandem mass spectrometry data	claim
476	91	A machine learning approach for the identification of odorant binding proteins from sequence-derived properties	claim
477	91	Graphs in molecular biology	claim
478	90	Gene network interconnectedness and the generalized topological overlap measure	claim
479	89	Primique: automatic design of specific PCR primers for each sequence in a family	claim
480	89	msmsEval: tandem mass spectral quality assignment for high-throughput proteomics	claim
481	89	Comparing segmentations by applying randomization techniques	claim
482	89	Selective prediction of interaction sites in protein structures with THEMATICS	claim
483	89	Highlights from the Third International Society for Computational Biology Student Council Symposium at the Fifteenth Annual International Conference on Intelligent Systems for Molecular Biolog	claim
484	89	Combining dissimilarity based classifiers for cancer prediction using gene expression profiles	claim
485	88	Computational analysis of the relationship between allergenicity and digestibility of allergenic proteins in simulated gastric fluid	claim
486	88	TMM@: a web application for the analysis of transmembrane helix mobility	claim
487	88	Use of DNA melting simulation software for in silico diagnostic assay design: targeting regions with complex melting curves and confirmation by real-time PCR using intercalating dyes	claim
488	88	BioCAD: an information fusion platform for bio-network inference and analysis	claim
489	87	'Unite and conquer': enhanced prediction of protein subcellular localization by integrating multiple specialized tools	claim
490	87	A manually curated database of tetrapod mitochondrially encoded tRNA sequences and secondary structures	claim
491	87	Preliminary nanopore cheminformatics analysis of aptamer-target binding strength	claim
492	86	Detecting microsatellites within genomes: significant variation among algorithms	claim
493	86	Importance of data structure in comparing two dimension reduction methods for classification of microarray gene expression data	claim
494	86	Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of MX-treated Salmonella	claim
495	86	Automated group assignment in large phylogenetic trees using GRUNT: GRouping, Ungrouping, Naming Tool	claim
496	86	Tandem mass spectrometry data quality assessment by self-convolution	claim
497	86	3'-UTR SIRF: A database for identifying clusters of short interspersed repeats in 3' untranslated regions	claim
498	84	A comparative study of S/MAR prediction tools	claim
499	84	Statistical analysis of genomic protein family and domain controlled annotations for functional investigation of classified gene lists	claim
500	83	Identification of sequence motifs significantly associated with antisense activity	claim
501	83	ChIP-on-chip significance analysis reveals ubiquitous transcription factor binding	claim
502	82	Visualization of three-way comparisons of omics data	claim
503	82	Glycosylation site prediction using ensembles of Support Vector Machine classifiers	claim
504	82	Predicting peptides binding to MHC class II molecules using multi-objective evolutionary algorithms	claim
505	82	From biophysics to evolutionary genetics: statistical aspects of gene regulation	claim
506	81	PADB : Published Association Database	claim
507	80	A network perspective on the topological importance of enzymes and their phylogenetic conservation	claim
508	80	AT excursion: a new approach to predict replication origins in viral genomes by locating AT-rich regions	claim
509	80	Predicting gene ontology functions from protein's regional surface structures	claim
510	80	Mining expression-dependent modules in the human interaction network	claim
511	79	Orthology prediction at scalable resolution by phylogenetic tree analysis	claim
512	79	Simcluster: clustering enumeration gene expression data on the simplex space	claim
513	79	Genomic scale analysis of lateral gene transfer in Apicomplexan parasites: insights into early eukaryotic evolution, host-pathogen interaction and drug target development	claim
514	79	Semi-supervised class discovery using quantitative phenotypes - CVD as a case study	claim
515	78	Improved human disease candidate gene prioritization using mouse phenotype	claim
516	77	Effective selection of informative SNPs and classification on the HapMap genotype data	claim
517	77	The reactive metabolite target protein database (TPDB) - a web-accessible resource	claim
518	77	Estimation of the number of extreme pathways for metabolic networks	claim
519	77	A systematic strategy for the discovery of candidate genes responsible for phenotypic variation	claim
520	76	Background frequencies for residue variability estimates: BLOSUM revisited	claim
521	75	Using indirect protein interactions for the prediction of Gene Ontology functions	claim
522	74	GraphDNA: a Java program for graphical display of DNA composition analyses	claim
523	74	A feature selection approach for identification of signature genes from SAGE data	claim
524	74	TAMEE: data management and analysis for tissue microarrays	claim
525	74	Detection of the inferred interaction network in hepatocellular carcinoma from EHCO (Encyclopedia of Hepatocellular Carcinoma genes Online)	claim
526	71	AYUMS: an algorithm for completely automatic quantitation based on LC-MS/MS proteome data and its application to the analysis of signal transduction	claim
527	71	Locational distribution of gene functional classes in Arabidopsis thaliana	claim
528	70	SAT, a flexible and optimized Web application for SSR marker development	claim
529	69	Improved precision and accuracy for microarrays using updated probe set definitions	claim
530	69	Unexpected observations after mapping LongSAGE tags to the human genome	claim
531	69	Homology modeling of a voltage-gated potassium channel (human Kv7.1)	claim
532	69	Gene function prediction based on genomic context clustering and discriminative learning: an application to bacteriophages	claim
533	68	In silico segmentations of lentivirus envelope sequences	claim
534	66	Accurate multiple sequence-structure alignment of RNA sequences using combinatorial optimization	claim
535	65	Identification of candidate regulatory sequences in mammalian 3' UTRs by statistical analysis of oligonucleotide distributions	claim
536	65	Scoring functions and enrichment: a case study on Hsp90	claim
537	65	Analysis of circadian pattern reveals tissue-specific alternative transcription in leptin signaling pathway	claim
538	64	Post hoc pattern matching: assigning significance to statistically defined expression patterns in single channel microarray data	claim
539	64	A transversal approach to predict gene product networks from ontology-based similarity	claim
540	64	Evaluation of sample size effect on the identification of haplotype blocks	claim
541	64	VSGdb: a database for trypanosome variant surface glycoproteins, a large and diverse family of coiled coil proteins	claim
542	64	Improved functional prediction of proteins by learning kernel combinations in multilabel settings	claim
543	63	Prediction of the burial status of transmembrane residues of helical membrane proteins	claim
544	63	Domain motions of Argonaute, the catalytic engine of RNA interference	claim
545	63	Least-squares methods for identifying biochemical regulatory networks from noisy measurements	claim
546	63	Introduction to semantic e-Science in biomedicine	claim
547	62	Missing channels in two-colour microarray experiments: Combining single-channel and two-channel data	claim
548	62	Weighted analysis of general microarray experiments	claim
549	62	ProtQuant: a tool for the label-free quantification of MudPIT proteomics data	claim
550	61	TBMap: a taxonomic perspective on the phylogenetic database TreeBASE	claim
551	60	Identifications of conserved 7-mers in 3'-UTRs and microRNAs in Drosophila	claim
552	60	BGX: a Bioconductor package for the Bayesian integrated analysis of Affymetrix GeneChips	claim
553	59	MASPECTRAS: a platform for management and analysis of proteomics LC-MS/MS data	claim
554	59	Environment specific substitution tables for thermophilic proteins	claim
555	58	Framework for a Protein Ontology	claim
556	57	Large-scale integration of cancer microarray data identifies a robust common cancer signature	claim
557	55	ProbCD: enrichment analysis accounting for categorization uncertainty	claim
558	55	Inference of miRNA targets using evolutionary conservation and pathway analysis	claim
559	51	A survey of orphan enzyme activities	claim
560	50	A general strategy to determine the congruence between a hierarchical and a non-hierarchical classification	claim
561	48	NIPS workshop on New Problems and Methods in Computational Biology	claim
562	45	Regulation of metabolic networks by small molecule metabolites	claim

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