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» A Bernoulli-Gaussian model for gene factor analysis
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NIPS
2008
13 years 9 months ago
A mixture model for the evolution of gene expression in non-homogeneous datasets
We address the challenge of assessing conservation of gene expression in complex, non-homogeneous datasets. Recent studies have demonstrated the success of probabilistic models in...
Gerald Quon, Yee Whye Teh, Esther Chan, Timothy R....
GCB
2008
Springer
103views Biometrics» more  GCB 2008»
13 years 8 months ago
Utilizing Promoter Pair Orientations for HMM-based Analysis of ChIP-chip Data
: Array-based analysis of chromatin immunoprecipitation data (ChIP-chip) is a powerful technique for identifying DNA target regions of individual transcription factors. Here, we pr...
Michael Seifert, Jens Keilwagen, Marc Strickert, I...
BMCBI
2006
131views more  BMCBI 2006»
13 years 7 months ago
SIMAGE: simulation of DNA-microarray gene expression data
Background: Simulation of DNA-microarray data serves at least three purposes: (i) optimizing the design of an intended DNA microarray experiment, (ii) comparing existing pre-proce...
Casper J. Albers, Ritsert C. Jansen, Jan Kok, Osca...
RECOMB
2012
Springer
11 years 9 months ago
Recovering the Tree-Like Trend of Evolution Despite Extensive Lateral Genetic Transfer: A Probabilistic Analysis
Abstract. Lateral gene transfer (LGT) is a common mechanism of nonvertical evolution where genetic material is transferred between two more or less distantly related organisms. It ...
Sebastien Roch, Sagi Snir
BMCBI
2007
169views more  BMCBI 2007»
13 years 7 months ago
Transcriptional regulatory network refinement and quantification through kinetic modeling, gene expression microarray data and i
Background: Gene expression microarray and other multiplex data hold promise for addressing the challenges of cellular complexity, refined diagnoses and the discovery of well-targ...
Abdallah Sayyed-Ahmad, Kagan Tuncay, Peter J. Orto...