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» A Case Study in the use of ROC curves for Algorithm Design
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BMCBI
2007
140views more  BMCBI 2007»
13 years 7 months ago
Prediction potential of candidate biomarker sets identified and validated on gene expression data from multiple datasets
Background: Independently derived expression profiles of the same biological condition often have few genes in common. In this study, we created populations of expression profiles...
Michael Gormley, William Dampier, Adam Ertel, Bilg...
BMCBI
2006
85views more  BMCBI 2006»
13 years 7 months ago
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
Rui Jiang, Hua Yang, Fengzhu Sun, Ting Chen
CORR
2011
Springer
183views Education» more  CORR 2011»
12 years 11 months ago
Learning When Training Data are Costly: The Effect of Class Distribution on Tree Induction
For large, real-world inductive learning problems, the number of training examples often must be limited due to the costs associated with procuring, preparing, and storing the tra...
Foster J. Provost, Gary M. Weiss
BMCBI
2010
123views more  BMCBI 2010»
13 years 7 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...
ICSEA
2009
IEEE
14 years 2 months ago
Testing of Image Processing Algorithms on Synthetic Data
—In this paper, it is shown that synthetic images can be used to test specific use cases of a lane tracking algorithm which has been developed by Audi AG. This was achieved by s...
Kilian von Neumann-Cosel, Erwin Roth, Daniel Lehma...