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BMCBI
2007
140views more  BMCBI 2007»
13 years 7 months ago
From genes to functional classes in the study of biological systems
Background: With the popularisation of high-throughput techniques, the need for procedures that help in the biological interpretation of results has increased enormously. Recently...
Fátima Al-Shahrour, Leonardo Arbiza, Hern&a...
BMCBI
2005
127views more  BMCBI 2005»
13 years 7 months ago
Genomes are covered with ubiquitous 11 bp periodic patterns, the "class A flexible patterns"
Background: The genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a g...
Etienne Larsabal, Antoine Danchin
TC
2010
13 years 2 months ago
Model-Driven System Capacity Planning under Workload Burstiness
In this paper, we define and study a new class of capacity planning models called MAP queueing networks. MAP queueing networks provide the first analytical methodology to describe ...
Giuliano Casale, Ningfang Mi, Evgenia Smirni
BMCBI
2011
12 years 11 months ago
A hierarchical Bayesian network approach for linkage disequilibrium modeling and data-dimensionality reduction prior to genome-w
Background: Discovering the genetic basis of common genetic diseases in the human genome represents a public health issue. However, the dimensionality of the genetic data (up to 1...
Raphael Mourad, Christine Sinoquet, Philippe Leray
BMCBI
2008
179views more  BMCBI 2008»
13 years 7 months ago
Building pathway clusters from Random Forests classification using class votes
Background: Recent years have seen the development of various pathway-based methods for the analysis of microarray gene expression data. These approaches have the potential to bri...
Herbert Pang, Hongyu Zhao