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» A Comparative Analysis of Dependence Testing Mechanisms
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BMCBI
2004
169views more  BMCBI 2004»
13 years 7 months ago
A power law global error model for the identification of differentially expressed genes in microarray data
Background: High-density oligonucleotide microarray technology enables the discovery of genes that are transcriptionally modulated in different biological samples due to physiolog...
Norman Pavelka, Mattia Pelizzola, Caterina Vizzard...
BMCBI
2005
132views more  BMCBI 2005»
13 years 7 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
BIOINFORMATICS
2011
12 years 11 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
ICAC
2009
IEEE
14 years 2 months ago
Ranking the importance of alerts for problem determination in large computer systems
The complexity of large computer systems has raised unprecedented challenges for system management. In practice, operators often collect large volume of monitoring data from system...
Guofei Jiang, Haifeng Chen, Kenji Yoshihira, Akhil...
DNA
2009
Springer
173views Bioinformatics» more  DNA 2009»
14 years 2 months ago
Time-Complexity of Multilayered DNA Strand Displacement Circuits
Recently we have shown how molecular logic circuits with many components arranged in multiple layers can be built using DNA strand displacement reactions. The potential application...
Georg Seelig, David Soloveichik