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» A Comparison of Genetic Network Models
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WABI
2009
Springer
155views Bioinformatics» more  WABI 2009»
14 years 1 months ago
A Markov Classification Model for Metabolic Pathways
Background: This paper considers the problem of identifying pathways through metabolic networks that relate to a specific biological response. Our proposed model, HME3M, first ide...
Timothy Hancock, Hiroshi Mamitsuka
GECCO
2006
Springer
165views Optimization» more  GECCO 2006»
13 years 10 months ago
Comparing mathematical models on the problem of network inference
In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of different mathemat...
Christian Spieth, Nadine Hassis, Felix Streichert
BMCBI
2011
12 years 10 months ago
A hierarchical Bayesian network approach for linkage disequilibrium modeling and data-dimensionality reduction prior to genome-w
Background: Discovering the genetic basis of common genetic diseases in the human genome represents a public health issue. However, the dimensionality of the genetic data (up to 1...
Raphael Mourad, Christine Sinoquet, Philippe Leray
ISMB
1996
13 years 8 months ago
The Mathematical Model of Subtractive Hybridization and Its Practical Application
A novel theory of subtractive hybridization including (or based on) the kinetic model of this process was proposed. A computer program modeling the process of subtraction wasdevel...
Olga D. Ermolaeva, Sergey A. Lukyanov, Eugene D. S...
JCB
2002
131views more  JCB 2002»
13 years 6 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong