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BIOSYSTEMS
2008
83views more  BIOSYSTEMS 2008»
13 years 7 months ago
Hydrophobic condensation and modular assembly model of protein folding
Despite several decades of intense study, protein folding problem remains elusive. In this paper, we review current knowledge and the prevailing thinking in the field, and summari...
Tian-Yow Tsong, Chin-Kun Hu, Ming-Chya Wu
BMCBI
2007
144views more  BMCBI 2007»
13 years 7 months ago
Application of amino acid occurrence for discriminating different folding types of globular proteins
Background: Predicting the three-dimensional structure of a protein from its amino acid sequence is a long-standing goal in computational/molecular biology. The discrimination of ...
Y.-h. Taguchi, M. Michael Gromiha
BMCBI
2007
119views more  BMCBI 2007»
13 years 7 months ago
Efficacy of different protein descriptors in predicting protein functional families
Background: Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a ne...
Serene A. K. Ong, Hong Huang Lin, Yu Zong Chen, Ze...
BMCBI
2007
115views more  BMCBI 2007»
13 years 7 months ago
Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry
Background: Structure elucidation of unknown small molecules by mass spectrometry is a challenge despite advances in instrumentation. The first crucial step is to obtain correct e...
Tobias Kind, Oliver Fiehn
TKDE
1998
122views more  TKDE 1998»
13 years 7 months ago
The Design and Implementation of Seeded Trees: An Efficient Method for Spatial Joins
—Existing methods for spatial joins require pre-existing spatial indices or other precomputation, but such approaches are inefficient and limited in generality. Operand data sets...
Ming-Ling Lo, Chinya V. Ravishankar