Sciweavers

485 search results - page 32 / 97
» A Computational Approach to Reconstructing Gene Regulatory N...
Sort
View
RECOMB
2010
Springer
13 years 9 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
PKDD
2004
Springer
113views Data Mining» more  PKDD 2004»
14 years 1 months ago
Discovery of Regulatory Connections in Microarray Data
Abstract. In this paper, we introduce a new approach for mining regulatory interactions between genes in microarray time series studies. A number of preprocessing steps transform t...
Michael Egmont-Petersen, Wim de Jonge, Arno Siebes
BMCBI
2010
240views more  BMCBI 2010»
13 years 8 months ago
CircuitsDB: a database of mixed microRNA/transcription factor feed-forward regulatory circuits in human and mouse
Background: Transcription Factors (TFs) and microRNAs (miRNAs) are key players for gene expression regulation in higher eukaryotes. In the last years, a large amount of bioinforma...
Olivier Friard, Angela Re, Daniela Taverna, Michel...
GI
2009
Springer
14 years 14 days ago
Massively-Parallel Simulation of Biochemical Systems
: Understanding biological evolution prompts for a detailed understanding of the realized phenotype. Biochemical and gene regulatory dynamics are a cornerstone for the physiology o...
Jens Ackermann, Paul Baecher, Thorsten Franzel, Mi...
RECOMB
2009
Springer
14 years 8 months ago
A Robust Bayesian Two-Sample Test for Detecting Intervals of Differential Gene Expression in Microarray Time Series
Abstract. Understanding the regulatory mechanisms that are responsible for an organism's response to environmental changes is an important question in molecular biology. A fir...
Oliver Stegle, Katherine J. Denby, David L. Wild, ...