Sciweavers

485 search results - page 4 / 97
» A Computational Approach to Reconstructing Gene Regulatory N...
Sort
View
RECOMB
2005
Springer
14 years 8 months ago
Causal Inference of Regulator-Target Pairs by Gene Mapping of Expression Phenotypes
Background: Correlations between polymorphic markers and observed phenotypes provide the basis for mapping traits in quantitative genetics. When the phenotype is gene expression, ...
David Kulp, Manjunatha Jagalur
BMCBI
2010
156views more  BMCBI 2010»
13 years 7 months ago
Global screening of potential Candida albicans biofilm-related transcription factors via network comparison
Background: Candida albicans is a commonly encountered fungal pathogen in humans. The formation of biofilm is a major virulence factor in C. albicans pathogenesis and is related t...
Yu-Chao Wang, Chung-Yu Lan, Wen-Ping Hsieh, Luis A...
RECOMB
2007
Springer
14 years 8 months ago
Learning Gene Regulatory Networks via Globally Regularized Risk Minimization
Learning the structure of a gene regulatory network from time-series gene expression data is a significant challenge. Most approaches proposed in the literature to date attempt to ...
Yuhong Guo, Dale Schuurmans
CMSB
2006
Springer
13 years 11 months ago
Incorporating Time Delays into the Logical Analysis of Gene Regulatory Networks
Based on the logical description of gene regulatory networks developed by R. Thomas, we introduce an enhanced modelling approach that uses timed automata. It yields a refined quali...
Heike Siebert, Alexander Bockmayr
BIOCOMP
2009
13 years 9 months ago
Inferring Gene Regulatory Networks from Asynchronous Microarray Data
Modern approaches to treating genetic disorders, cancers and even epidemics rely on a detailed understanding of the underlying gene signaling network. Previous work has used time s...
David Oviatt, Mark J. Clement, Quinn Snell, Kennet...