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» A Computational Model for RNA Multiple Structural Alignment.
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ISMB
1993
13 years 10 months ago
Using Dirichlet Mixture Priors to Derive Hidden Markov Models for Protein Families
A Bayesian method for estimating the amino acid distributions in the states of a hidden Markov model (HMM) for a protein familyor the columns of a multiple alignment of that famil...
Michael Brown, Richard Hughey, Anders Krogh, I. Sa...
BMCBI
2005
123views more  BMCBI 2005»
13 years 8 months ago
PSI-BLAST-ISS: an intermediate sequence search tool for estimation of the position-specific alignment reliability
Background: Protein sequence alignments have become indispensable for virtually any evolutionary, structural or functional study involving proteins. Modern sequence search and com...
Mindaugas Margelevicius, Ceslovas Venclovas
MEDINFO
2007
139views Healthcare» more  MEDINFO 2007»
13 years 10 months ago
Lessons Learned from Cross-Validating Alignments between Large Anatomical Ontologies
Objectives: To compare the alignments of two large anatomical ontologies (the Foundational Model of Anatomy and GALEN) produced by three ontology alignment systems (AOAS, FALCON a...
Songmao Zhang, Olivier Bodenreider
RECOMB
2006
Springer
14 years 9 months ago
A Parameterized Algorithm for Protein Structure Alignment
This paper proposes a parameterized algorithm for aligning two protein structures, in the case where one protein structure is represented by a contact map graph and the other by a ...
Jinbo Xu, Feng Jiao, Bonnie Berger
BMCBI
2010
176views more  BMCBI 2010»
13 years 9 months ago
TargetSpy: a supervised machine learning approach for microRNA target prediction
Background: Virtually all currently available microRNA target site prediction algorithms require the presence of a (conserved) seed match to the 5' end of the microRNA. Recen...
Martin Sturm, Michael Hackenberg, David Langenberg...