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» A DIAMOND Method for Classifying Biological Data
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BMCBI
2010
179views more  BMCBI 2010»
13 years 7 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
BMCBI
2008
116views more  BMCBI 2008»
13 years 7 months ago
The combination approach of SVM and ECOC for powerful identification and classification of transcription factor
Background: Transcription factors (TFs) are core functional proteins which play important roles in gene expression control, and they are key factors for gene regulation network co...
Guangyong Zheng, Ziliang Qian, Qing Yang, Chaochun...
BMCBI
2008
200views more  BMCBI 2008»
13 years 7 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
RECOMB
2007
Springer
14 years 7 months ago
An Efficient and Accurate Graph-Based Approach to Detect Population Substructure
Currently, large-scale projects are underway to perform whole genome disease association studies. Such studies involve the genotyping of hundreds of thousands of SNP markers. One o...
Srinath Sridhar, Satish Rao, Eran Halperin
BMCBI
2010
208views more  BMCBI 2010»
13 years 7 months ago
Using machine learning to speed up manual image annotation: application to a 3D imaging protocol for measuring single cell gene
Background: Image analysis is an essential component in many biological experiments that study gene expression, cell cycle progression, and protein localization. A protocol for tr...
Zafer Aydin, John I. Murray, Robert H. Waterston, ...