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BMCBI
2010
113views more  BMCBI 2010»
15 years 4 months ago
Use of historic metabolic biotransformation data as a means of anticipating metabolic sites using MetaPrint2D and Bioclipse
Background: Predicting metabolic sites is important in the drug discovery process to aid in rapid compound optimisation. No interactive tool exists and most of the useful tools ar...
Lars Carlsson, Ola Spjuth, Samuel Adams, Robert C....
JMLR
2010
134views more  JMLR 2010»
14 years 11 months ago
Bayesian Algorithms for Causal Data Mining
We present two Bayesian algorithms CD-B and CD-H for discovering unconfounded cause and effect relationships from observational data without assuming causal sufficiency which prec...
Subramani Mani, Constantin F. Aliferis, Alexander ...
NN
2007
Springer
15 years 10 months ago
Impact of Higher-Order Correlations on Coincidence Distributions of Massively Parallel Data
The signature of neuronal assemblies is the higher-order correlation structure of the spiking activity of the participating neurons. Due to the rapid progress in recording technol...
Sonja Grün, Moshe Abeles, Markus Diesmann
BMCBI
2008
323views more  BMCBI 2008»
15 years 4 months ago
A compatible exon-exon junction database for the identification of exon skipping events using tandem mass spectrum data
Background: Alternative splicing is an important gene regulation mechanism. It is estimated that about 74% of multi-exon human genes have alternative splicing. High throughput tan...
Fan Mo, Xu Hong, Feng Gao, Lin Du, Jun Wang, Gilbe...
PPOPP
2010
ACM
16 years 1 months ago
Scalable communication protocols for dynamic sparse data exchange
Many large-scale parallel programs follow a bulk synchronous parallel (BSP) structure with distinct computation and communication phases. Although the communication phase in such ...
Torsten Hoefler, Christian Siebert, Andrew Lumsdai...