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» A Database Platform for Bioinformatics
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BIB
2010
103views more  BIB 2010»
13 years 6 months ago
Challenges of sequencing human genomes
Massively parallel sequencing technologies continue to alter the study of human genetics. As the cost of sequencing declines, next-generation sequencing (NGS) instruments and data...
Daniel C. Koboldt, Li Ding, Elaine R. Mardis, Rich...
BMCBI
2008
106views more  BMCBI 2008»
13 years 9 months ago
An Integrated Korean Biodiversity and Genetic Information Retrieval System
Background: On-line biodiversity information databases are growing quickly and being integrated into general bioinformatics systems due to the advances of fast gene sequencing tec...
Jeongheui Lim, Jong Bhak, Hee-Mock Oh, Chang-Bae K...
BMCBI
2006
135views more  BMCBI 2006»
13 years 9 months ago
Correcting ligands, metabolites, and pathways
Background: A wide range of research areas in bioinformatics, molecular biology and medicinal chemistry require precise chemical structure information about molecules and reaction...
Martin A. Ott, Gert Vriend
BIBE
2008
IEEE
142views Bioinformatics» more  BIBE 2008»
14 years 3 months ago
Optimizing performance, cost, and sensitivity in pairwise sequence search on a cluster of PlayStations
— The Smith-Waterman algorithm is a dynamic programming method for determining optimal local alignments between nucleotide or protein sequences. However, it suffers from quadrati...
Ashwin M. Aji, Wu-chun Feng
CSB
2004
IEEE
135views Bioinformatics» more  CSB 2004»
14 years 1 months ago
Selection of Patient Samples and Genes for Outcome Prediction
Gene expression profiles with clinical outcome data enable monitoring of disease progression and prediction of patient survival at the molecular level. We present a new computatio...
Huiqing Liu, Jinyan Li, Limsoon Wong