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» A Database Platform for Bioinformatics
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ISDA
2006
IEEE
14 years 3 months ago
From Gene to Drug: A Proof of Concept for a Plausible Computational Pathway
The last decade has witnessed an exponential growth of sequence information in the field of biological macromolecules such as proteins and nucleic acids and their interactions wit...
Sandhya Shenoy, B. Jayaram, N. Latha, Pooja Narang...
CHI
2010
ACM
14 years 4 months ago
G-nome surfer: a tabletop interface for collaborative exploration of genomic data
Molecular and computational biologists develop new insights by gathering heterogeneous data from genomic databases and leveraging bioinformatics tools. Through a qualitative study...
Orit Shaer, Guy Kol, Megan Strait, Chloe Fan, Cath...
BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
13 years 9 months ago
Helix Interaction Tool (HIT): a web-based tool for analysis of helix-helix interactions in proteins
Motivation: In many proteins, helix-helix interactions can be critical to establishing protein conformation (folding) and dynamics, as well as determining associations between pro...
Anne E. Counterman Burba, Ursula Lehnert, Eric Z. ...
BIOINFORMATICS
2006
135views more  BIOINFORMATICS 2006»
13 years 9 months ago
Effective similarity measures for expression profiles
It is commonly accepted that genes with similar expression profiles are functionally related. However, there are many ways one can measure the similarity of expression profiles, a...
Golan Yona, William Dirks, Shafquat Rahman, David ...
BIOINFORMATICS
2006
129views more  BIOINFORMATICS 2006»
13 years 9 months ago
Predicting methylation status of CpG islands in the human brain
Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
Fang Fang, Shicai Fan, Xuegong Zhang, Michael Q. Z...