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    BMCBI
    2010
    89views more  BMCBI 2010»
    Semi-automatic identification of punching areas for tissue microarray building: the tubular breast cancer pilot study
    13 years 8 months ago
    Semi-automatic identification of punching areas for tissue microarray building: the tubular breast cancer pilot study
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    Background: Tissue MicroArray technology aims to perform immunohistochemical staining on hundreds of different tissue samples simultaneously. It allows faster analysis, considerab...
    Federica Viti, Ivan Merelli, Mieke Timmermans, Mic...
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    BMCBI
    2007
    102views more  BMCBI 2007»
    Multivariate Analysis and Visualization of Splicing Correlations in Single-Gene Transcriptomes
    13 years 8 months ago
    Multivariate Analysis and Visualization of Splicing Correlations in Single-Gene Transcriptomes
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    Background: RNA metabolism, through 'combinatorial splicing', can generate enormous structural diversity in the proteome. Alternative domains may interact, however, with...
    Mark C. Emerick, Giovanni Parmigiani, William S. A...
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    BMCBI
    2008
    116views more  BMCBI 2008»
    The combination approach of SVM and ECOC for powerful identification and classification of transcription factor
    13 years 8 months ago
    The combination approach of SVM and ECOC for powerful identification and classification of transcription factor
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    Background: Transcription factors (TFs) are core functional proteins which play important roles in gene expression control, and they are key factors for gene regulation network co...
    Guangyong Zheng, Ziliang Qian, Qing Yang, Chaochun...
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    BMCBI
    2008
    179views more  BMCBI 2008»
    Bayesian modeling of recombination events in bacterial populations
    13 years 8 months ago
    Bayesian modeling of recombination events in bacterial populations
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    Background: We consider the discovery of recombinant segments jointly with their origins within multilocus DNA sequences from bacteria representing heterogeneous populations of fa...
    Pekka Marttinen, Adam Baldwin, William P. Hanage, ...
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    BMCBI
    2008
    159views more  BMCBI 2008»
    Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via log
    13 years 8 months ago
    Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via log
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    Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
    Dawei Liu, Debashis Ghosh, Xihong Lin
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