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BMCBI
2006
137views more  BMCBI 2006»
13 years 10 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
BMCBI
2006
144views more  BMCBI 2006»
13 years 10 months ago
Association algorithm to mine the rules that govern enzyme definition and to classify protein sequences
Background: The number of sequences compiled in many genome projects is growing exponentially, but most of them have not been characterized experimentally. An automatic annotation...
Shih-Hau Chiu, Chien-Chi Chen, Gwo-Fang Yuan, Thy-...
DATAMINE
2006
127views more  DATAMINE 2006»
13 years 10 months ago
Computing LTS Regression for Large Data Sets
Least trimmed squares (LTS) regression is based on the subset of h cases (out of n) whose least squares t possesses the smallest sum of squared residuals. The coverage h may be se...
Peter Rousseeuw, Katrien van Driessen
BMCBI
2007
120views more  BMCBI 2007»
13 years 10 months ago
Non-coding sequence retrieval system for comparative genomic analysis of gene regulatory elements
Background: Completion of the human genome sequence along with other species allows for greater understanding of the biochemical mechanisms and processes that govern healthy as we...
Sung Tae Doh, Yunyu Zhang, Matthew H. Temple, Li C...
BMCBI
2007
136views more  BMCBI 2007»
13 years 10 months ago
Comparison of protein structures by growing neighborhood alignments
Background: Design of protein structure comparison algorithm is an important research issue, having far reaching implications. In this article, we describe a protein structure com...
Sourangshu Bhattacharya, Chiranjib Bhattacharyya, ...