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BMCBI
2007
130views more  BMCBI 2007»
13 years 10 months ago
HMM-ModE - Improved classification using profile hidden Markov models by optimising the discrimination threshold and modifying e
Background: Profile Hidden Markov Models (HMM) are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have b...
Prashant K. Srivastava, Dhwani K. Desai, Soumyadee...
BMCBI
2010
148views more  BMCBI 2010»
13 years 10 months ago
Structuring heterogeneous biological information using fuzzy clustering of k-partite graphs
Background: Extensive and automated data integration in bioinformatics facilitates the construction of large, complex biological networks. However, the challenge lies in the inter...
Mara L. Hartsperger, Florian Blöchl, Volker S...
BMCBI
2010
134views more  BMCBI 2010»
13 years 10 months ago
Localizing triplet periodicity in DNA and cDNA sequences
Background: The protein-coding regions (coding exons) of a DNA sequence exhibit a triplet periodicity (TP) due to fact that coding exons contain a series of three nucleotide codon...
Liya Wang, Lincoln D. Stein
BMCBI
2008
130views more  BMCBI 2008»
13 years 10 months ago
FAF-Drugs2: Free ADME/tox filtering tool to assist drug discovery and chemical biology projects
Background: Drug discovery and chemical biology are exceedingly complex and demanding enterprises. In recent years there are been increasing awareness about the importance of pred...
David Lagorce, Olivier Sperandio, Hervé Gal...
CN
2010
160views more  CN 2010»
13 years 10 months ago
ABS: Adaptive buffer sizing for heterogeneous networks
Most existing criteria [3], [5], [8] for sizing router buffers rely on explicit formulation of the relationship between buffer size and characteristics of Internet traffic. However...
Yueping Zhang, Dmitri Loguinov