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JCB
2007
144views more  JCB 2007»
13 years 7 months ago
Statistical Estimation of Statistical Mechanical Models: Helix-Coil Theory and Peptide Helicity Prediction
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...
RECOMB
2003
Springer
14 years 7 months ago
Modeling dependencies in protein-DNA binding sites
The availability of whole genome sequences and high-throughput genomic assays opens the door for in silico analysis of transcription regulation. This includes methods for discover...
Yoseph Barash, Gal Elidan, Nir Friedman, Tommy Kap...
BMCBI
2004
158views more  BMCBI 2004»
13 years 7 months ago
Improvement of alignment accuracy utilizing sequentially conserved motifs
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...
ISMB
1994
13 years 8 months ago
Optimally Parsing a Sequence into Different Classes Based on Multiple Types of Evidence
Weconsider the problem of parsing a sequence into different classes of subsequences.Twocommonexamplesare finding the exons and introns in genomicsequences and identifying the seco...
Gary D. Stormo, David Haussler
RECOMB
2006
Springer
14 years 7 months ago
Simulating Protein Motions with Rigidity Analysis
Abstract. Protein motions, ranging from molecular flexibility to largescale conformational change, play an essential role in many biochemical processes. Despite the explosion in ou...
Shawna L. Thomas, Xinyu Tang, Lydia Tapia, Nancy M...