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BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
Gene function classification using Bayesian models with hierarchy-based priors
We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
Babak Shahbaba, Radford M. Neal
BMCBI
2004
196views more  BMCBI 2004»
13 years 7 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar
BMCBI
2010
154views more  BMCBI 2010»
13 years 7 months ago
An eScience-Bayes strategy for analyzing omics data
Background: The omics fields promise to revolutionize our understanding of biology and biomedicine. However, their potential is compromised by the challenge to analyze the huge da...
Martin Eklund, Ola Spjuth, Jarl E. S. Wikberg
TIP
2010
182views more  TIP 2010»
13 years 2 months ago
Flexible Manifold Embedding: A Framework for Semi-Supervised and Unsupervised Dimension Reduction
We propose a unified manifold learning framework for semi-supervised and unsupervised dimension reduction by employing a simple but effective linear regression function to map the ...
Feiping Nie, Dong Xu, Ivor Wai-Hung Tsang, Changsh...
BMCBI
2006
172views more  BMCBI 2006»
13 years 7 months ago
BioWarehouse: a bioinformatics database warehouse toolkit
Background: This article addresses the problem of interoperation of heterogeneous bioinformatics databases. Results: We introduce BioWarehouse, an open source toolkit for construc...
Thomas J. Lee, Yannick Pouliot, Valerie Wagner, Pr...