Background: The accuracy of protein secondary structure prediction has been improving steadily towards the 88% estimated theoretical limit. There are two types of prediction algor...
Gene functions is an essential knowledge for understanding how metabolism works and designing treatments for solving malfunctions. The Modular Multi-Relational Framework (MMRF) is ...
Background: Methods are now available for the prediction of interaction sites in protein 3D structures. While many of these methods report high success rates for site prediction, ...
Ying Wei, Jaeju Ko, Leonel F. Murga, Mary Jo Ondre...
Background: Structure prediction of membrane proteins is still a challenging computational problem. Hidden Markov models (HMM) have been successfully applied to the problem of pre...
Piero Fariselli, Pier Luigi Martelli, Rita Casadio
Prediction of protein secondary structure (alpha-helix, beta-sheet, coil) from primary sequence of amino acids is a very challenging task, and the problem has been approached from...