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    BMCBI
    2008
    178views more  BMCBI 2008»
    Identification of coherent patterns in gene expression data using an efficient biclustering algorithm and parallel coordinate vi
    13 years 8 months ago
    Identification of coherent patterns in gene expression data using an efficient biclustering algorithm and parallel coordinate vi
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    Background: The DNA microarray technology allows the measurement of expression levels of thousands of genes under tens/hundreds of different conditions. In microarray data, genes ...
    Kin-On Cheng, Ngai-Fong Law, Wan-Chi Siu, Alan Wee...
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    BMCBI
    2004
    146views more  BMCBI 2004»
    Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
    13 years 8 months ago
    Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
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    Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
    Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
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    BMCBI
    2008
    98views more  BMCBI 2008»
    GBNet: Deciphering regulatory rules in the co-regulated genes using a Gibbs sampler enhanced Bayesian network approach
    13 years 8 months ago
    GBNet: Deciphering regulatory rules in the co-regulated genes using a Gibbs sampler enhanced Bayesian network approach
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    Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
    Li Shen, Jie Liu, Wei Wang
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    BMCBI
    2005
    102views more  BMCBI 2005»
    Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computatio
    13 years 8 months ago
    Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computatio
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    Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
    Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...
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    RECOMB
    2003
    Springer
    181views Computational Biology» more  RECOMB 2003»
    An integrated probabilistic model for functional prediction of proteins
    14 years 9 months ago
    An integrated probabilistic model for functional prediction of proteins
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    We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
    Minghua Deng, Ting Chen, Fengzhu Sun
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