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» A Gene Network Model for Developing Cell Lineages
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BMCBI
2007
114views more  BMCBI 2007»
13 years 7 months ago
Mining and state-space modeling and verification of sub-networks from large-scale biomolecular networks
Background: Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As ...
Xiaohua Hu, Fang-Xiang Wu
BMCBI
2008
122views more  BMCBI 2008»
13 years 7 months ago
Reconstructing networks of pathways via significance analysis of their intersections
Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...
Mirko Francesconi, Daniel Remondini, Nicola Nerett...
IJON
2000
62views more  IJON 2000»
13 years 7 months ago
A large-scale model of the cerebellar cortex using PGENESIS
In an investigation into the transformation of mossy ber input to Purkinje cell output in the cerebellar cortex, we have developed a network model including a sophisticated compar...
F. W. Howell, Jonas Dyhrfjeld-Johnsen, Reinoud Mae...
LSMS
2007
Springer
14 years 1 months ago
A Simulation Study on the Encoding Mechanism of Retinal Ganglion Cell
Understanding how the retina encodes visual information is a key issue for the development of a retinal prosthesis. To study this issue, the neural retina is modeled as a retina mo...
Chao-Feng Cai, Pei-Ji Liang, Pu-Ming Zhang
BMCBI
2005
126views more  BMCBI 2005»
13 years 7 months ago
HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms
Background: The application of high throughput approaches to the identification of protein interactions has offered for the first time a glimpse of the global interactome of some ...
Maria Persico, Arnaud Ceol, Caius Gavrila, Robert ...