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BMCBI
2007
78views more  BMCBI 2007»
13 years 7 months ago
Improved human disease candidate gene prioritization using mouse phenotype
Background: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-thro...
Jing Chen, Huan Xu, Bruce J. Aronow, Anil G. Jegga
CVPR
2004
IEEE
14 years 9 months ago
Feature Selection for Classifying High-Dimensional Numerical Data
Classifying high-dimensional numerical data is a very challenging problem. In high dimensional feature spaces, the performance of supervised learning methods suffer from the curse...
Yimin Wu, Aidong Zhang
BMCBI
2011
13 years 2 months ago
SNP-based pathway enrichment analysis for genome-wide association studies
Background: Recently we have witnessed a surge of interest in using genome-wide association studies (GWAS) to discover the genetic basis of complex diseases. Many genetic variatio...
Lingjie Weng, Fabio Macciardi, Aravind Subramanian...
ISMB
2000
13 years 9 months ago
Pattern Recognition of Genomic Features with Microarrays: Site Typing of Mycobacterium Tuberculosis Strains
Mycobacterium tuberculosis (M. tb.) strains differ in the number and locations of a transposon-like insertion sequence known as IS6110. Accurate detection of this sequence can be ...
Soumya Raychaudhuri, Joshua M. Stuart, Xuemin Liu,...
GECCO
2007
Springer
197views Optimization» more  GECCO 2007»
14 years 2 months ago
Computational intelligence techniques: a study of scleroderma skin disease
This paper presents an analysis of microarray gene expression data from patients with and without scleroderma skin disease using computational intelligence and visual data mining ...
Julio J. Valdés, Alan J. Barton