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BMCBI
2005
103views more  BMCBI 2005»
13 years 7 months ago
SeqDoC: rapid SNP and mutation detection by direct comparison of DNA sequence chromatograms
Background: This paper describes SeqDoC, a simple, web-based tool to carry out direct comparison of ABI sequence chromatograms. This allows the rapid identification of single nucl...
Mark L. Crowe
BMCBI
2005
77views more  BMCBI 2005»
13 years 7 months ago
Combining Affymetrix microarray results
Background: As the use of microarray technology becomes more prevalent it is not unusual to find several laboratories employing the same microarray technology to identify genes re...
John R. Stevens, R. W. Doerge
BMCBI
2004
180views more  BMCBI 2004»
13 years 7 months ago
Noise filtering and nonparametric analysis of microarray data underscores discriminating markers of oral, prostate, lung, ovaria
Background: A major goal of cancer research is to identify discrete biomarkers that specifically characterize a given malignancy. These markers are useful in diagnosis, may identi...
Virginie M. Aris, Michael J. Cody, Jeff Cheng, Jam...
BMCBI
2004
112views more  BMCBI 2004»
13 years 7 months ago
MuTrack: a genome analysis system for large-scale mutagenesis in the mouse
Background: Modern biological research makes possible the comprehensive study and development of heritable mutations in the mouse model at high-throughput. Using techniques spanni...
Erich J. Baker, Leslie Galloway, Barbara Jackson, ...
BMCBI
2004
106views more  BMCBI 2004»
13 years 7 months ago
Spotting effect in microarray experiments
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
Tristan Mary-Huard, Jean-Jacques Daudin, Sté...