MuTrack: a genome analysis system for large-scale mutagenesis in the mouse

Background: Modern biological research makes possible the comprehensive study and development of heritable mutations in the mouse model at high-throughput. Using techniques spanning genetics, molecular biology, histology, and behavioral science, researchers may examine, with varying degrees of granularity, numerous phenotypic aspects of mutant mouse strains directly pertinent to human disease states. Success of these and other genome-wide endeavors relies on a well-structured bioinformatics core that brings together investigators from widely dispersed institutions and enables them to seamlessly integrate data, observations and discussions. Description: MuTrack was developed as the bioinformatics core for a large mouse phenotype screening effort. It is a comprehensive collection of on-line computational tools and tracks thousands of mutagenized mice from birth through senescence and death. It identifies the physical location of mice during an intensive phenotype screening process at se...

• Type: Journal
• Year: 2004
• Where: BMCBI
• Authors: Erich J. Baker, Leslie Galloway, Barbara Jackson, Denise Schmoyer, Jay Snoddy
• Keywords: BMCBI 2004, Large Mouse Phenotype, Mouse, Mutant Mouse