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JAMIA
2011
98views more  JAMIA 2011»
12 years 10 months ago
Mapping clinical phenotype data elements to standardized metadata repositories and controlled terminologies: the eMERGE Network
Background Systematic study of clinical phenotypes is important for a better understanding of the genetic basis of human diseases and more effective gene-based disease management....
Jyotishman Pathak, Janey Wang, Sudha Kashyap, Meli...
BMCBI
2008
141views more  BMCBI 2008»
13 years 7 months ago
MiRTif: a support vector machine-based microRNA target interaction filter
Background: MicroRNAs (miRNAs) are a set of small non-coding RNAs serving as important negative gene regulators. In animals, miRNAs turn down protein translation by binding to the...
Yuchen Yang, Yu-Ping Wang, Kuo-Bin Li
BMCBI
2006
184views more  BMCBI 2006»
13 years 7 months ago
PubFocus: semantic MEDLINE/PubMed citations analytics through integration of controlled biomedical dictionaries and ranking algo
Background: Understanding research activity within any given biomedical field is important. Search outputs generated by MEDLINE/PubMed are not well classified and require lengthy ...
Maksim V. Plikus, Zina Zhang, Cheng-Ming Chuong
BMCBI
2008
88views more  BMCBI 2008»
13 years 7 months ago
Large-scale identification of polymorphic microsatellites using an in silico approach
Background: Simple Sequence Repeat (SSR) or microsatellite markers are valuable for genetic research. Experimental methods to develop SSR markers are laborious, time consuming and...
Jifeng Tang, Samantha J. Baldwin, Jeanne M. E. Jac...
NAR
2010
143views more  NAR 2010»
13 years 2 months ago
WormBase: a comprehensive resource for nematode research
WormBase (http://www.wormbase.org) is a central data repository for nematode biology. Initially created as a service to the Caenorhabditis elegans research field, WormBase has evo...
Todd W. Harris, Igor Antoshechkin, Tamberlyn Bieri...