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» A Graph Theoretic Approach to Protein Structure Selection
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113
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BMCBI
2010
116views more  BMCBI 2010»
15 years 3 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
150
Voted
TIT
2010
170views Education» more  TIT 2010»
14 years 10 months ago
Belief propagation estimation of protein and domain interactions using the sum-product algorithm
We present a novel framework to estimate protein-protein (PPI) and domain-domain (DDI) interactions based on a belief propagation estimation method that efficiently computes inter...
Faruck Morcos, Marcin Sikora, Mark S. Alber, Dale ...
134
Voted
ENC
2004
IEEE
15 years 7 months ago
A New Cache Approach Based on Graph for Web Servers
This article deals with the problem of data cache for dynamic web servers. A set of requests (which number could be large) is submitted to a server for computing. Every request is...
Euloge Edi, Denis Trystram, Jean-Marc Vincent
125
Voted
RELMICS
2000
Springer
15 years 7 months ago
A Relational View of Subgraph Isomorphism
This paper presents a novel approach to the problem of finding all subgraph isomorphisms of a (pattern) graph into another (target) graph. A relational formulation of the problem, ...
Jordi Cortadella, Gabriel Valiente
113
Voted
ECAL
2007
Springer
15 years 10 months ago
Emergence of Genetic Coding: An Information-Theoretic Model
This paper1 introduces a simple model for evolutionary dynamics approaching the “coding threshold”, where the capacity to symbolically represent nucleic acid sequences emerges ...
Piraveenan Mahendra, Daniel Polani, Mikhail Prokop...