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» A Graph Theoretic Approach to Protein Structure Selection
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BMCBI
2010
116views more  BMCBI 2010»
13 years 8 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
TIT
2010
170views Education» more  TIT 2010»
13 years 3 months ago
Belief propagation estimation of protein and domain interactions using the sum-product algorithm
We present a novel framework to estimate protein-protein (PPI) and domain-domain (DDI) interactions based on a belief propagation estimation method that efficiently computes inter...
Faruck Morcos, Marcin Sikora, Mark S. Alber, Dale ...
ENC
2004
IEEE
14 years 10 days ago
A New Cache Approach Based on Graph for Web Servers
This article deals with the problem of data cache for dynamic web servers. A set of requests (which number could be large) is submitted to a server for computing. Every request is...
Euloge Edi, Denis Trystram, Jean-Marc Vincent
RELMICS
2000
Springer
14 years 5 days ago
A Relational View of Subgraph Isomorphism
This paper presents a novel approach to the problem of finding all subgraph isomorphisms of a (pattern) graph into another (target) graph. A relational formulation of the problem, ...
Jordi Cortadella, Gabriel Valiente
ECAL
2007
Springer
14 years 2 months ago
Emergence of Genetic Coding: An Information-Theoretic Model
This paper1 introduces a simple model for evolutionary dynamics approaching the “coding threshold”, where the capacity to symbolically represent nucleic acid sequences emerges ...
Piraveenan Mahendra, Daniel Polani, Mikhail Prokop...