Background: Protein aggregation correlates with the development of several debilitating human disorders of growing incidence, such as Alzheimer's and Parkinson's disease...
Background: Data mining in large DNA sequences is a major challenge in microbial genomics and bioinformatics. Oligonucleotide usage (OU) patterns provide a wealth of information f...
Hamilton Ganesan, Anna S. Rakitianskaia, Colin F. ...
Tree models are valuable tools for predictive modeling and data mining. Traditional tree-growing methodologies such as CART are known to suffer from problems including greediness,...
Background: The regulatory map of a genome consists of the binding sites for proteins that determine the transcription of nearby genes. An initial regulatory map for S. cerevisiae...
Kenzie D. MacIsaac, Ting Wang, D. Benjamin Gordon,...
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...