Background: Predicting the suppression activity of antisense oligonucleotide sequences is the main goal of the rational design of nucleic acids. To create an effective predictive ...
Abstract. We introduce a concept of similarity between vertices of directed graphs. Let GA and GB be two directed graphs with respectively nA and nB vertices. We define a nA × nB...
Background: Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionall...
Anne M. Denton, Jianfei Wu, Megan K. Townsend, Pre...
In the k-medoid problem, given a dataset P, we are asked to choose k points in P as the medoids. The optimal medoid set minimizes the average Euclidean distance between the points ...
Background: Cluster analysis is an integral part of high dimensional data analysis. In the context of large scale gene expression data, a filtered set of genes are grouped togethe...