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BIOSYSTEMS
2007
111views more  BIOSYSTEMS 2007»
13 years 11 months ago
A Markovian approach to the control of genetic regulatory networks
This paper presents an approach for controlling gene networks based on a Markov chain model, where the state of a gene network is represented as a probability distribution, while ...
Peter C. Y. Chen, Jeremy W. Chen
GECCO
2005
Springer
178views Optimization» more  GECCO 2005»
14 years 4 months ago
A co-evolutionary hybrid algorithm for multi-objective optimization of gene regulatory network models
In this paper, the parameters of a genetic network for rice flowering time control have been estimated using a multiobjective genetic algorithm approach. We have modified the rece...
Praveen Koduru, Sanjoy Das, Stephen Welch, Judith ...
ECAI
2008
Springer
14 years 24 days ago
Temporal Logic Patterns for Querying Qualitative Models of Genetic Regulatory Networks
Formal verification based on model checking provides a powerful technology to query qualitative models of dynamical systems. The application of model-checking approaches is hamper...
Pedro T. Monteiro, Delphine Ropers, Radu Mateescu,...
BMCBI
2007
186views more  BMCBI 2007»
13 years 11 months ago
Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms
Background: Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as...
Jung-Hsien Chiang, Shih-Yi Chao
HYBRID
2007
Springer
14 years 5 months ago
Model Checking Genetic Regulatory Networks with Parameter Uncertainty
The lack of precise numerical information for the values of biological parameters severely limits the development and analysis of models of genetic regulatory networks. To deal wit...
Grégory Batt, Calin Belta, Ron Weiss