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» A Methodology for Comparative Functional Genomics
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BMCBI
2010
150views more  BMCBI 2010»
13 years 8 months ago
DeltaProt: a software toolbox for comparative genomics
Background: Statistical bioinformatics is the study of biological data sets obtained by new micro-technologies by means of proper statistical methods. For a better understanding o...
Steinar Thorvaldsen, Tor Flå, Nils Willassen
BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
13 years 8 months ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...
BMCBI
2008
156views more  BMCBI 2008»
13 years 8 months ago
Chromhome: A rich internet application for accessing comparative chromosome homology maps
Background: Comparative genomics has become a significant research area in recent years, following the availability of a number of sequenced genomes. The comparison of genomes is ...
Sridevi Nagarajan, Willem Rens, James Stalker, Ton...
BMCBI
2006
124views more  BMCBI 2006»
13 years 8 months ago
Predicting transcription factor binding sites using local over-representation and comparative genomics
Background: Identifying cis-regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented tran...
Matthieu Defrance, Hélène Touzet
BMCBI
2005
133views more  BMCBI 2005»
13 years 8 months ago
Systematic determination of the mosaic structure of bacterial genomes: species backbone versus strain-specific loops
Background: Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to add...
Hélène Chiapello, I. Bourgait, F. So...