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127
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: Efforts to predict functional sites from globular proteins is increasingly common; however, the most successful of these methods generally require structural insight. ...
128
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
138
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Computational approaches to this problem ...
158
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
147
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: Gene expression measurements during the development of the fly Drosophila melanogaster are routinely used to find functional modules of temporally co-expressed genes. ...