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» A Multi-metric Similarity Based Analysis of Microarray Data
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BMCBI
2007
168views more  BMCBI 2007»
13 years 7 months ago
GOSim - an R-package for computation of information theoretic GO similarities between terms and gene products
Background: With the increased availability of high throughput data, such as DNA microarray data, researchers are capable of producing large amounts of biological data. During the...
Holger Fröhlich, Nora Speer, Annemarie Poustk...
BMCBI
2007
130views more  BMCBI 2007»
13 years 7 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
ACAL
2007
Springer
14 years 1 months ago
An Integrated QAP-Based Approach to Visualize Patterns of Gene Expression Similarity
Abstract. This paper illustrates how the Quadratic Assignment Problem (QAP) is used as a mathematical model that helps to produce a visualization of microarray data, based on the r...
Mario Inostroza-Ponta, Alexandre Mendes, Regina Be...
BMCBI
2008
138views more  BMCBI 2008»
13 years 7 months ago
Novel implementation of conditional co-regulation by graph theory to derive co-expressed genes from microarray data
Background: Most existing transcriptional databases like Comprehensive Systems-Biology Database (CSB.DB) and Arabidopsis Microarray Database and Analysis Toolbox (GENEVESTIGATOR) ...
Arun Rawat, Georg J. Seifert, Youping Deng
BMCBI
2008
124views more  BMCBI 2008»
13 years 7 months ago
Literature-aided meta-analysis of microarray data: a compendium study on muscle development and disease
Background: Comparative analysis of expression microarray studies is difficult due to the large influence of technical factors on experimental outcome. Still, the identified diffe...
Rob Jelier, Peter A. C. 't Hoen, Ellen Sterrenburg...