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PCI
2005
Springer
14 years 29 days ago
Protein Classification with Multiple Algorithms
Nowadays, the number of protein sequences being stored in central protein databases from labs all over the world is constantly increasing. From these proteins only a fraction has b...
Sotiris Diplaris, Grigorios Tsoumakas, Pericles A....
BMCBI
2007
124views more  BMCBI 2007»
13 years 7 months ago
Protein structural similarity search by Ramachandran codes
Background: Protein structural data has increased exponentially, such that fast and accurate tools are necessary to access structure similarity search. To improve the search speed...
Wei-Cheng Lo, Po-Jung Huang, Chih-Hung Chang, Ping...
ALGORITHMICA
1999
84views more  ALGORITHMICA 1999»
13 years 7 months ago
Computational Approaches to Drug Design
Abstract. The rational approach to pharmaceutical drug design begins with an investigation of the relationship between chemical structure and biological activity. Information gaine...
Paul W. Finn, Lydia E. Kavraki
BMCBI
2005
115views more  BMCBI 2005»
13 years 7 months ago
SUPERFICIAL - Surface mapping of proteins via structure-based peptide library design
Background: The determination of protein surfaces and the detection of binding sites are essential to our understanding of protein-protein interactions. Such binding sites can be ...
Andrean Goede, Ines S. Jaeger, Robert Preissner
BMCBI
2007
102views more  BMCBI 2007»
13 years 7 months ago
FlexOracle: predicting flexible hinges by identification of stable domains
Background: Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions i...
Samuel Flores, Mark Gerstein