77 search results - page 5 / 16 » A Multi-strategy Approach to Protein Structural Alphabet Des... |
117
Voted
PCI
2005
Springer
15 years 9 months ago
2005
Springer
Nowadays, the number of protein sequences being stored in central protein databases from labs all over the world is constantly increasing. From these proteins only a fraction has b...
170
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: Protein structural data has increased exponentially, such that fast and accurate tools are necessary to access structure similarity search. To improve the search speed...
114
Voted
ALGORITHMICA
1999
15 years 3 months ago
1999
Abstract. The rational approach to pharmaceutical drug design begins with an investigation of the relationship between chemical structure and biological activity. Information gaine...
129
Voted
BMCBI
2005
15 years 3 months ago
2005
Background: The determination of protein surfaces and the detection of binding sites are essential to our understanding of protein-protein interactions. Such binding sites can be ...
119
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions i...