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BMCBI
2011
15 years 28 days ago
A novel approach to the clustering of microarray data via nonparametric density estimation
Background: Cluster analysis is a crucial tool in several biological and medical studies dealing with microarray data. Such studies pose challenging statistical problems due to di...
Riccardo De Bin, Davide Risso
BMCBI
2011
15 years 28 days ago
A quality metric for homology modeling: the H-factor
Background: The analysis of protein structures provides fundamental insight into most biochemical functions and consequently into the cause and possible treatment of diseases. As ...
Eric di Luccio, Patrice Koehl
BMCBI
2011
15 years 28 days ago
Simulated evolution applied to study the genetic code optimality using a model of codon reassignments
Background: As the canonical code is not universal, different theories about its origin and organization have appeared. The optimization or level of adaptation of the canonical ge...
Jose Santos, Ángel Monteagudo
BMCBI
2011
15 years 28 days ago
Multiclass classification of microarray data samples with a reduced number of genes
Background: Multiclass classification of microarray data samples with a reduced number of genes is a rich and challenging problem in Bioinformatics research. The problem gets hard...
Elizabeth Tapia, Leonardo Ornella, Pilar Bulacio, ...
BMCBI
2011
15 years 28 days ago
Taxon ordering in phylogenetic trees: a workbench test
Background: Phylogenetic trees are an important tool for representing evolutionary relationships among organisms. In a phylogram or chronogram, the ordering of taxa is not conside...
Francesco Cerutti, Luigi Bertolotti, Tony L. Goldb...
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