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NIPS
2008
13 years 10 months ago
Scalable Algorithms for String Kernels with Inexact Matching
We present a new family of linear time algorithms based on sufficient statistics for string comparison with mismatches under the string kernels framework. Our algorithms improve t...
Pavel P. Kuksa, Pai-Hsi Huang, Vladimir Pavlovic
BMCBI
2007
233views more  BMCBI 2007»
13 years 8 months ago
160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
Isaac T. S. Li, Warren Shum, Kevin Truong
IPPS
2006
IEEE
14 years 2 months ago
FPGA based architecture for DNA sequence comparison and database search
DNA sequence comparison is a computationally intensive problem, known widely since the competition for human DNA decryption. Database search for DNA sequence comparison is of grea...
Euripides Sotiriades, Christos Kozanitis, Apostolo...
TCBB
2008
126views more  TCBB 2008»
13 years 8 months ago
Graphical Models of Residue Coupling in Protein Families
Abstract-- Many statistical measures and algorithmic techniques have been proposed for studying residue coupling in protein families. Generally speaking, two residue positions are ...
John Thomas, Naren Ramakrishnan, Chris Bailey-Kell...
BMCBI
2005
90views more  BMCBI 2005»
13 years 8 months ago
TMB-Hunt: An amino acid composition based method to screen proteomes for beta-barrel transmembrane proteins
Background: Beta-barrel transmembrane (bbtm) proteins are a functionally important and diverse group of proteins expressed in the outer membranes of bacteria (both gram negative a...
Andrew G. Garrow, Alison Agnew, David R. Westhead