The increasing availability of interaction graphs requires new resource-efficient tools capable of extracting valuable biological knowledge from these networks. In this paper we ...
Markov Clustering (MCL) is a popular algorithm for clustering networks in bioinformatics such as protein-protein interaction networks and protein similarity networks. An important...
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...
Background: Pairwise sequence alignment methods are widely used in biological research. The increasing number of sequences is perceived as one of the upcoming challenges for seque...
Jacek Blazewicz, Wojciech Frohmberg, Michal Kierzy...
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...