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BMCBI
2007
198views more  BMCBI 2007»
13 years 8 months ago
Correlation analysis reveals the emergence of coherence in the gene expression dynamics following system perturbation
Time course gene expression experiments are a popular means to infer co-expression. Many methods have been proposed to cluster genes or to build networks based on similarity measu...
Nicola Neretti, Daniel Remondini, Marc Tatar, John...
IWC
2011
111views more  IWC 2011»
13 years 3 months ago
Socio-technical systems: From design methods to systems engineering
The importance of adopting a socio-technical approach to system development is recognised by many but not widely practised. We analyse the reasons for this, considering the histor...
Gordon D. Baxter, Ian Sommerville
BMCBI
2010
201views more  BMCBI 2010»
13 years 9 months ago
Analysis of X-ray Structures of Matrix Metalloproteinases via Chaotic Map Clustering
Background: Matrix metalloproteinases (MMPs) are well-known biological targets implicated in tumour progression, homeostatic regulation, innate immunity, impaired delivery of pro-...
Ilenia Giangreco, Orazio Nicolotti, Angelo Carotti...
BMCBI
2010
164views more  BMCBI 2010»
13 years 9 months ago
Flexible network reconstruction from relational databases with Cytoscape and CytoSQL
Background: Molecular interaction networks can be efficiently studied using network visualization software such as Cytoscape. The relevant nodes, edges and their attributes can be...
Kris Laukens, Jens Hollunder, Thanh Hai Dang, Geer...
BMCBI
2010
108views more  BMCBI 2010»
13 years 9 months ago
A genetic ensemble approach for gene-gene interaction identification
Background: It has now become clear that gene-gene interactions and gene-environment interactions are ubiquitous and fundamental mechanisms for the development of complex diseases...
Pengyi Yang, Joshua W. K. Ho, Albert Y. Zomaya, Bi...