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» A New Approach to Protein Structure Mining and Alignment
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BMCBI
2002
133views more  BMCBI 2002»
13 years 8 months ago
Identification and characterization of subfamily-specific signatures in a large protein superfamily by a hidden Markov model app
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...
Kevin Truong, Mitsuhiko Ikura
NAR
2007
152views more  NAR 2007»
13 years 8 months ago
COMPASS server for remote homology inference
COMPASS is a method for homology detection and local alignment construction based on the comparison of multiple sequence alignments (MSAs). The method derives numerical profiles f...
Ruslan Sadreyev, Ming Tang, Bong-Hyun Kim, Nick V....
BMCBI
2006
125views more  BMCBI 2006»
13 years 8 months ago
Automated functional classification of experimental and predicted protein structures
Background: Proteins that are similar in sequence or structure may perform different functions in nature. In such cases, function cannot be inferred from sequence or structural si...
Kai Wang, Ram Samudrala
BMCBI
2005
140views more  BMCBI 2005»
13 years 8 months ago
JACOP: A simple and robust method for the automated classification of protein sequences with modular architecture
Background: Whole-genome sequencing projects are rapidly producing an enormous number of new sequences. Consequently almost every family of proteins now contains hundreds of membe...
Peter Sperisen, Marco Pagni
BMCBI
2005
162views more  BMCBI 2005»
13 years 8 months ago
Accelerated probabilistic inference of RNA structure evolution
Background: Pairwise stochastic context-free grammars (Pair SCFGs) are powerful tools for evolutionary analysis of RNA, including simultaneous RNA sequence alignment and secondary...
Ian Holmes