Sciweavers

563 search results - page 34 / 113
» A New Approach to Protein Structure Mining and Alignment
Sort
View
BMCBI
2010
129views more  BMCBI 2010»
13 years 8 months ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas
BMCBI
2004
196views more  BMCBI 2004»
13 years 8 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar
CONSTRAINTS
2008
95views more  CONSTRAINTS 2008»
13 years 8 months ago
Efficient Sequence Alignment with Side-Constraints by Cluster Tree Elimination
Aligning DNA and protein sequences is a core technique in molecular biology. Often, it is desirable to include partial prior knowledge and conditions in an alignment. Going beyond...
Sebastian Will, Anke Busch, Rolf Backofen
GECCO
2004
Springer
137views Optimization» more  GECCO 2004»
14 years 1 months ago
Evolving Better Multiple Sequence Alignments
Aligning multiple DNA or protein sequences is a fundamental step in the analyses of phylogeny, homology and molecular structure. Heuristic algorithms are applied because optimal mu...
Luke Sheneman, James A. Foster
COLING
2002
13 years 8 months ago
Structure Alignment Using Bilingual Chunking
A new statistical method called "bilingual chunking" for structure alignment is proposed. Different with the existing approaches which align hierarchical structures like...
Wei Wang, Ming Zhou, Jin-Xia Huang, Changning Huan...