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» A New Approach to Protein Structure Mining and Alignment
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SEMWEB
2007
Springer
14 years 2 months ago
SODA: an OWL-DL based Ontology Matching System
This paper describes SODA a novel ontology alignment method for the OWL-DL format. SODA uses a new approach that consists in computing local and semantic similarities among ontolog...
Sami Zghal, Sadok Ben Yahia, Engelbert Mephu Nguif...
BMCBI
2007
99views more  BMCBI 2007»
13 years 8 months ago
Identifying allosteric fluctuation transitions between different protein conformational states as applied to Cyclin Dependent Ki
Background: The mechanisms underlying protein function and associated conformational change are dominated by a series of local entropy fluctuations affecting the global structure ...
Jenny Gu, Philip E. Bourne
IPPS
2009
IEEE
14 years 3 months ago
Parallel reconstruction of neighbor-joining trees for large multiple sequence alignments using CUDA
Computing large multiple protein sequence alignments using progressive alignment tools such as ClustalW requires several hours on state-of-the-art workstations. ClustalW uses a th...
Yongchao Liu, Bertil Schmidt, Douglas L. Maskell
BIOINFORMATICS
2005
140views more  BIOINFORMATICS 2005»
13 years 8 months ago
Profile-based direct kernels for remote homology detection and fold recognition
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
Huzefa Rangwala, George Karypis
BMCBI
2007
144views more  BMCBI 2007»
13 years 8 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...