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BMCBI
2007
157views more  BMCBI 2007»
13 years 7 months ago
Statistical learning of peptide retention behavior in chromatographic separations: a new kernel-based approach for computational
Background: High-throughput peptide and protein identification technologies have benefited tremendously from strategies based on tandem mass spectrometry (MS/MS) in combination wi...
Nico Pfeifer, Andreas Leinenbach, Christian G. Hub...
ICPR
2004
IEEE
14 years 8 months ago
Relaxation Labeling Processes for Protein Secondary Structure Prediction
The prediction of protein secondary structure is a classical problem in bioinformatics, and in the past few years several machine learning techniques have been proposed to t. From...
Giacomo Colle, Marcello Pelillo
BMCBI
2007
116views more  BMCBI 2007»
13 years 7 months ago
Clustering protein environments for function prediction: finding PROSITE motifs in 3D
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...
BMCBI
2008
112views more  BMCBI 2008»
13 years 7 months ago
A simplified approach to disulfide connectivity prediction from protein sequences
Background: Prediction of disulfide bridges from protein sequences is useful for characterizing structural and functional properties of proteins. Several methods based on differen...
Marc Vincent, Andrea Passerini, Matthieu Labb&eacu...
ICML
2007
IEEE
14 years 8 months ago
An integrated approach to feature invention and model construction for drug activity prediction
We present a new machine learning approach for 3D-QSAR, the task of predicting binding affinities of molecules to target proteins based on 3D structure. Our approach predicts bind...
David Page, Jesse Davis, Soumya Ray, Vítor ...