Background: The development of DNA microarrays has facilitated the generation of hundreds of thousands of transcriptomic datasets. The use of a common reference microarray design ...
Mark J. Alston, John Seers, Jay C. D. Hinton, Sach...
DNA microarrays have demonstrated an excellent potential in correlating specific gene expression profiles to specific conditions. However, they are affected by inherent noise. ...
Genetic instability represents an important type of biological markers for cancer and many other diseases. Array Comparative Genome Hybridization (aCGH) is a high-throughput cytoge...
Alternative splicing (AS) is an important and frequent step in mammalian gene expression that allows a single gene to specify multiple products, and is crucial for the regulation ...
Ofer Shai, Brendan J. Frey, Quaid Morris, Qun Pan,...
Background: In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one ...