Background: Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available metho...
William A. McLaughlin, Ken Chen, Tingjun Hou, Wei ...
Background: The prediction of ancestral protein sequences from multiple sequence alignments is useful for many bioinformatics analyses. Predicting ancestral sequences is not a sim...
Scalable similarity search is the core of many large scale learning or data mining applications. Recently, many research results demonstrate that one promising approach is creatin...
One goal of the structural genomics initiative is the identification of new protein folds. Sequence-based structural homology prediction methods are an important means for priorit...
Motivation: Evaluating the accuracy of predicted models is critical for assessing structure prediction methods. Because this problem is not trivial, a large number of different as...
Naomi Siew, Arne Elofsson, Leszek Rychlewski, Dani...