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BMCBI
2010
88views more  BMCBI 2010»
13 years 10 months ago
Proteome scanning to predict PDZ domain interactions using support vector machines
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
Shirley Hui, Gary D. Bader
BMCBI
2007
157views more  BMCBI 2007»
13 years 10 months ago
Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory
Background: Large-scale sequencing of entire genomes has ushered in a new age in biology. One of the next grand challenges is to dissect the cellular networks consisting of many i...
Feng Luo, Yunfeng Yang, Jianxin Zhong, Haichun Gao...
BMCBI
2008
166views more  BMCBI 2008»
13 years 10 months ago
Learning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual informa
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...
Weijun Luo, Kurt D. Hankenson, Peter J. Woolf
CORR
2008
Springer
193views Education» more  CORR 2008»
13 years 10 months ago
Faster and better: a machine learning approach to corner detection
The repeatability and efficiency of a corner detector determines how likely it is to be useful in a real-world application. The repeatability is importand because the same scene vi...
Edward Rosten, Reid Porter, Tom Drummond
BMCBI
2006
100views more  BMCBI 2006»
13 years 9 months ago
Design of microarray probes for virus identification and detection of emerging viruses at the genus level
Background: Most virus detection methods are geared towards the detection of specific single viruses or just a few known targets, and lack the capability to uncover the novel viru...
Cheng-Chung Chou, Te-Tsui Lee, Chun-Houh Chen, Hsi...